61 results
Antisense oligoribonucleotides inducing exon skipping is a promising approach to restore dystrophin synthesis in patients with Duchenne.
Goal: 1. Defining normal electophysiologic matarution in premature infants by quantitative analysing techniques; 2. Identifying circumstances that disturb normal electrophysiologic maturation.
The optimal management of locoregionally advanced NSCLC is evolving. Multimodality treatment is rapidly becoming the most common approach to stage III NSCLC. ASCO guidelines recommend initial chemotherapy (platinum-based, 2 or 3 cycles) combined…
rt-PA administration by retinal branch vein way in CRVO patients improves final BCVA.
Children born small for gestational age (SGA) might be at increased risk for developing hypertension, cardiovascular disease and diabetes mellitus type 2. It has been shown that those SGA children with relatively higher GH levels during an overnight…
To determine the influence of oral medicinal cannabis on the pharmacokinetics of irinotecan and docetaxel and their respective metabolites in cancer patients.
Comparison of two new techniques for detection of small bowel pathology: MR enteroclysis and videocapsule enteroscopy with double-balloon enteroscopy with respect to diagnostic yield, accuracy of findings, and patient preference.
HIV infected patients receiving HAART have an increased risk for cardiac events/disease. In HAART naive patients increased arterial stiffness is substrate for this higher risk. In this study we investigate whether increased risk for cardiac events…
Specific behavioural symptoms of dementia needs specific treatment. In cases, Levetiracetam seems to be effective in Non-psychotic and Non-depressive behavioural symptoms of dementia.
There a two research questions: 1. Do Self-instructions lead to a significant decrease of fatigue and functional impairments of CFS patiente compared to a waiting list condition? 2. For which patients are Self-instructions a suitable treatment…
Based on studies in other types of cancer in humans where beneficial effects were obtained, and based on our pre-clinical data in a mouse model for malignant mesothelioma (MM), it now seems feasible and warranted to introduce dendritic cell (DC)-…
The prevalence of Growth Hormone Deficiency in Autoimmune Thyroid Disease is higher than in the general population
Patients with Familial Hypobetalipoproteinemia (FHBL) could have increased hepatic glucose production because of hepatic steatosis. Additionally, peripheral insulin sensitivity could be enhanced since these patients have lower concentrations of…
p53 mutation in colorectal cancer provides an immunological window for immune therapy.
Non-inferiority hypothesis: observation is not inferior to operation with respect to the mean of pain and discomfort during 3 years follow-up.
Cultured mesenchymal stem cells differentiated into osteoblasts and seeded on scaffolds can induce bone formation.
The cold fenotype of CRPS1 is associated with a better respons to percutaneous sympathetic blockade as opposed to the warm type of CRPS1.
Mechanical bowel preparation (MBP) is common practice in elective colorectal surgery. In recent literature the value of MBP is subject of discussion. This non-inferiority, randomized study evaluates the value of MBP before colorectal surgery.
A specific set of variables of impairments are related/ predictive of functional limitations and disabilities. A specific set of variables of functional limitations are related/ predictive of disabilities. Psychological variables (defined by TPB,…
To evaluate the response to adalimumab treatment in TNF-alpha blockade naïve patients and patients who failed prior other anti-TNF-alpha treatment and to understand the mechanisms underlying the clinical response to TNF-alpha blockade.