282 results
Health outcomes for people at risk of or suffering from non-communicable lung diseases in low-resource settings will be improved by developing capacity for implementation of evidence-based interventions for prevention, diagnosis and treatment in…
MPS I patients can be treated with Aldurazyme safely and effectively.
For the prevention of diabetic foot ulceration, evidence exists to support the use of home-monitoring of foot skin temperature by means of a hand-held infrared skin thermometer. However, the construct validity of skin temperature measurements is…
Muscular counterpulsation (MCP) is a new treatment option which seems to improve hemodynamics but might also have positive effects on muscular and vascular function. Additionally, it is non-invasive and does not seem to have relevant side effects.…
An upfront RBCT aiming at low-normal Hb levels will ameliorate anemia-caused tumor hypoxia-related resistance to chemotherapy before the start of chemotherapy and may decrease secondary anemia-induced endogenous release of cytokines like VEGF,…
Null hypothesis: the 8 centres with different cardiac rehabilitation (CR) programmes do not differ from each other with regards to the effectiveness.
To investigate in an unselected memory clinic sample, the clinical value of 18F]FBB PET in terms of 1. change in diagnosis; 2. change in level of confidence of diagnosis; 3. impact on patient healthcare management.
The sensitivity and specificity of MDCTA for identifying coronary artery stenosis ¡Ý 50% in a patient with suspected coronary artery disease, is of equal quality compared with conventional coronary angiography.
Sentinel node mapping for bladder cancer is possible using the hybrid tracer ICG-99mTc-nanocolloid
The hypothesis is that a combination of exercise therapy and splinting is superior to splinting alone in the treatment of patients with thumb base osteoarthritis.
The invasive bacteria Shigella and entero-invasive E.coli (EIEC) that cause gastro-enteritis, are genetically related and share an infection mechanism. In the Netherlands, Shigellosis is a notifiable disease, while infections with EIEC are not. With…
Children with underlying medical conditions, prematurity and low birth weight are at increased risk of hospitalizations due to rotavirus (RV) gastroenteritis, RV related complications and mortality. In a recent Dutch study it was demonstrated that…
Succesful discontinuation of antipsychotics used for behavioural symptoms in people with intellectual disability is determined by staff-related factors and by neurological withdrawal symptoms.
We hypothesize that there is no difference in survival, clinical and radiological follow-up after >12 years of follow-up between the scarf and chevron osteotomy.
1. Comprehensive geriatric assessment has no benefits in selecting patients fit for chemotherapeutic treatment, compared to clinical judgement by the medical oncologist; 2. Observational report of the functional outcome of treating ovarian carcinoma…
Clients in a consumer-driven program for recovery, empowerment and experiential expertise will have better outcomes on self-efficacy and empowerment than clients on a waiting list for the program.
We expect that mp-MRI, molecular urine test and Prostate Cancer Risk Calculator may be of additional value in differentiating between significant and insignificant cancers in men with an elevated PSA in the primairy diagnosis. If so, it will result…
It will be investigated whether passive leg raising and stroke volume variations can be used in predicting renal responses to fluid administration. Our hypothesis is that dynamic predictors of cardiac fluid responsiveness can predict an increase in…