26 results
The effects of intravenous TRH administration on brown adipose tissue activity in healthy, lean men.
To investigate whether BAT tissue can be activated by intravenous administration of TRH. Secondary objectives are to determine whether intravenous TRH increases the degree of cardiovascular sympathetic stimulation and the response of skin…
To compare Bone Material Strength of the tibia at the side of a fracture or arhtrodesis with that of the opposite tibia in patients who had been immobilized for at least 6 weeks after a recently sustained fracture of the ankle of calcaneus or after…
1a. Compare fat endocrine function in obese fit versus obese unfit people under resting conditions and immediately after exercise.1b. Compare fat endocrine function in non-obese fit versus non-obese unfit people under resting conditions and…
Primary objective is: - To evaluate the effects of (controlled) dehydration on coagulation and fibrinolytic parameters.Secondary objectives are:- To evaluate whether the response of coagulation and fibrinolytic parameters to dehydration is mediated…
Primary objective is: - To evaluate the effects of dehydration and subsequent rehydration on coagulation and fibrinolytic parameters.Secondary objectives are:- To evaluate whether the response of coagulation and fibrinolytic parameters to fluid…
Primary Objective: To determine the differences in function and morphology of the distinct abdominal adipose tissue depots (e.g. SAT, PVAT, OAT and MAT; see figure 1) in patients undergoing elective open abdominal aortic surgery.Secondary…
To investigate if sunitinib has clinical significant activity in patients with metastatic/recurrent paraganglioma/pheochromocytoma.
Primary objectives is: - To evaluate the effects of dehydration (fluid deficit) on coagulation and fibrinolytic parametersSecondary objectives are:- To evaluate whether the response of coagulation and fibrinolytic parameters to dehydration is…
Primary objective is: - To evaluate the effects of dehydration and subsequent rehydration on coagulation and fibrinolytic parametersSecondary objectives are:- To evaluate whether the response of coagulation and fibrinolytic parameters to fluid…
Primary objective1.To determine the characteristics, frequency and severity of vascular, metabolic and hormonal side effects of angiogenesis inhibitors and EGFR inhibitors.Secondary objectives1.To investigate if steroid profile, indol profile,…
To determine if PHA-739358 has an antitumor activity against breast, ovaria, pancreatic, colerectal, small and non small cell squamous lung cancer.
Primary objective: To explore whether prolonged moderate alcohol consumption affects in vivo cytokine response after a low dose of LPS in young, normal-weight men.Secondary objectives: To explore whether prolonged moderate alcohol consumption-…
a. analysis of the usefulness of new molecular biological techniques in the diagnostic process of short stature, especially the detection of small chromosomal anomalies.b. identification of genetic factors causing short stature or influencing the…
The primary objective of this clinical controlled trial is to define the overall effect of adenocorticotropic hormone on coagulation parameters in patients with primary adrenal insufficiency (as diagnosed by their physician by previous short ACTH…
Primary objectives: Stress response: To determine whether acute alcohol consumption shortly after a psychological/mental stressor attenuates the stress response recovery.Cholinergic status: To determine whether prolonged moderate alcohol consumption…
To determine the additiotinal value of EUS and 11C-5-HTP PET scan for detection of pancreatic NET.
To investigate whether therapy with the tyrosine kinase inhibitor Sorafenib will increase the accumulation of radioiodine (RaI) and decrease tumor progression in patients with recurrences or metastases of non-medullary thyroid carcinoma with absent…
While this survey will provide information about mean LDL-C levels and the percent of patients at LDL-C goals, the survey will also focus on HDL-C. A primary objective of this survey is to assess the levels of HDL-C in treated dyslipidemic patients…
The primary aim for this study therefore is:1. To study the effects of an 8-week exercise training on RNA expression profiles in adipose tissue and skeletal muscle in obese individualsSecondarily we also aim:2. To relate changes in RNA expression…
1. To examine the effect of cold on post-prandial triglyceride metabolism using a standardized meal test during and after cold exposure 2. To examine the relationship between cold-induced brown adipose tissue activity and the changes in…