28 results
Primary: safety and tolerability of belimumab in a pediatric population (5-17 y) with SLE.Secondary: PK, efficacy, quality of life.
Investigate the value of percutaneous radiofrequency heat lesion, applied to the medial branch of the primary dorsal ramus; more specifically try to determine if a significant and long lasting pain reduction can be obtained as compared to a sham-…
Investigate the value of percutaneous radiofrequency heat lesion applied to the ramus communicans; more specifically try to determine if a significant and long lasting pain reduction can be obtained as compared to a sham-operated group. In addition…
To identify the brain and behavioral mechanisms via which oxytocin modulates communicative behavior.
To analyze the additional benefits of nebulization with a solution of NaCl or salbutamol after exercise by elite skaters in dry air in comparison to elite skaters not nebulising (controls). Reduced decrease in FEV1 after exercise by the verum group…
We expect that in people with multiple sclerosis the processing of energy substances such as sugars (energy metabolism)i n the brains is not optimal . In our view this could explain the progressive deterioration of the disease. Currently there are…
The major objective of the present study is to examine the acute effects of dietary plant stanol esters on the intestinal mucosal gene expression profiles in intestinal biopsies in healthy volunteers. Two minor objectives are (1) to investigate…
Objective: This study hypothesizes that an oxytocin inhalation will increase prosocial behavior and reduces social anxiety during social interaction specifically in patients with SAD in comparison to a clinical and healthy control group
The primary objective of this study is to test the hypothesis that risperidone given orally in a dose of 0.25 - 3.0 mg/d depending on body weight (eq. to approximately 0.01 - 0.04 mg/kg/d) for 12 weeks is superior to placebo in reducing disruptive…
The primary objective is to test the hypothesis that, after at least 15 weeks of daily administration (4 for titration, 7 of relatively stable dose, 4 at fixed doses; Study Period II), risperidone given orally in a dose of 0.25 - 3.0 mg/d depending…
The objectives of this study are to determine the safety and efficacy of IW-9179administered to patients with functional dyspepsia (FD), with and without concomitant protonpump inhibitor (PPI) administration.
To evaluate the efficacy of Arnica om postoperative outcome after upper blepharoplasty.
The aim of this study is therefore to investigate the role of the 5-HT2a receptor in the MDMA-induced effects on social behaviour.
to assess whether a single-dose of levodopa improves cognitive symptoms and balances goal-directed and habitual behavior.
Healthy volunteers and patients with a high variability in pain scores have a high probability to experience pain relief from alfentanil opposed to volunteers and patients with a low variability in pain scores.
Hypotheses: 1. That there will be a change in the negative sense in sensory stimulus processing after 2 weeks and possibly up to 3 months after anaesthesia as measured with I/T SP; 2. That there is a relation between postoperative changes as…
Intranasal insulin will improve development and behaviour in children with Phelan-McDermid syndrome.
Patients administered perioperative reversed local infiltration of ropivacaine will have lower pain scores, a faster rehabilitation, and lower cumulative consumption of (opioid-) pain medication postoperative, when compared to patients administered…
Motor cortex or cerebellar tDCS(transcranial Direct Current Stimulation) will enhance motor skill learning in heatlhy subjects and chronic stroke survivors. Stimulating the motor cortex will result in an increase in offline learning, whereas…
1. The deafferentiation during spinal anesthesia changes the connectivity in resting-state networks in healthy volunteers; 2. The deafferentiation during spinal anesthesia changes pain perception and has sedetive effects.