96 results
The primary objective is to investigate the effectiveness of a personalized 2-year multidomain lifestyle intervention on cognitive performance in older adults at risk of cognitive decline.
We expect better outcomes: ABC > CBM > sham-CBM
We hypothesize that restoration of gut microbiota diversity (by using donor FMT enriched in Desulfovibrio strains) could have explicit beneficial effects on glucose metabolism and NAFLD (via improved fructose catabolism), which is driven by…
Our research objectives are two-fold: First we investigate whether nocebo effects can be learned via electrical pain conditioning and verbal suggestions. We expect that participants in the nocebo group, but not the control group, will report higher…
To reduce fatigue symptoms with the use of a bovine lactoferrin supplement in patients suffering from Long COVID.
The aim of this study is to prospectively assess the efficacy of LDN as induction therapy in CD.
A positive effect on mood is expected after LSD (20 µg) compared to placebo. The effect of LSD on mood is expected to differ depending on time of drug administration (morning vs evening).
Early IVIg treatment in addition to prednisone results in a meaningful clinical response in treatment naive myositis patients in the short term and increased HR-QoL in the long term
The null hypothesis states there is no difference in effectiveness of the ESPB compared to placebo on early postoperative pain intensity measured with NRS in patients that underwent lumbar spine fusion surgery.
Let µT denote the mean value of the composite IBS-SSS score under treatment with the active / GOS and µP denote the mean value of the composite IBS-SSS score under placebo, then the primary two-sided hypothesis to be tested is: • H0: µT - µP = 0 (i.…
In this study we will investigate whether changes in gutmicrobiota composition induced by allogenic donor fecal transplantation (from longterm type 1 diabetes mellitus patients with preserved beta cell function) compared to placebo, , has…
1. There will be a significant improvement in cognitive control, attention bias and memory bias performance after completion of the selected training module in the active vs. control training. 2. Rumination and depressive symptom severity will…
Rivastigmine will protect against the cognitive and memory side effects of ECT
This study has been transitioned to CTIS with ID 2023-506918-45-00 check the CTIS register for the current data. Primary objectiveTo confirm the superiority of oral semaglutide versus placebo on the change in cognition and function in subjects with…
This study has been transitioned to CTIS with ID 2024-517846-32-00 check the CTIS register for the current data. To evaluate the effect of prolonged duration of (fos)aprepitant prophylaxis on the prevention of delayed CINV (complete remission in the…
The objective of this Phase 3 study is to investigate the safety and efficacy of benralizumab as a treatment for patients with eosinophilic gastritis and/or gastro-enteritis.
This study has been transitioned to CTIS with ID 2023-506919-18-00 check the CTIS register for the current data. Primary objectiveTo confirm the superiority of oral semaglutide versus placebo on the change in cognition and function in subjects with…
The present study aims to assess the effectiveness of a religion-adapted CBM intervention compared to a standard, non-religion CBM intervention, and sham intervention based on approach bias modification (ApBM).
The aim of this study is to find a directly applicable intervention for acutely suicidal patients, so that the risk of these patients committing suicide is substantially lowered, leading to fewer actual suicides. To this end we propose a randomized…
This study has been transitioned to CTIS with ID 2023-509265-21-00 check the CTIS register for the current data. To evaluate safety and the effect of isolated limb perfusion together with nivolumab as a way to increase efficacy and give further…