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The use of perioperative antibiotic prophylaxis in the treatment of acute cholecystitis, a randomized, multicenter, non-inferiority trial

To provide high level of evidence that omitting perioperative antibiotic prophylaxis does not increase the postoperative infection rate, in patients with acute calculous cholecystitis undergoing laparoscopic cholecystectomy.

Evaluation of the Follow me mode of the AutoLap system- a feasibility study

The main objectives of this study are to evaluate the performance and ease of use of the Follow me mode of the AutoLap system during general and gynecological laparoscopic procedures.Study Procedures: No. & type. A total of 35 laparoscopic…

Acute cholecystitis in high risk patients: percutaneous cholecystostomy versus laparoscopic cholecystectomy; a randomized controlled, open, parallel, superiority, multicenter trial

To demonstrate that primary LC as compared to PC is preferable with respect to morbidity and mortality in high risk surgical patients (APACHE-II score 7-14) with acute calculous cholecystitis.

Kumar clamp versus Olsen cAtheter for Laparoscopic intraoperative cholAngiography (KOALA)

To assess whether cholangiography using the Kumar clamp is faster and easier than using the Olsen catheter.

Perioperative antibiotic use in the treatment of acute calculous cholecystitis

To demonstrate that extended postoperative antibiotic treatment does not decrease the infectious complication rate in laparoscopic cholecystectomy for acute cholecystitis.

Long term effect of bile duct injury in gallbladder surgery.

Evaluation of quality of life and resoration of function after bile duct injury.

Diagnostic accuracy of MRI for gallbladder polyps;
a prospective diagnostic pilot study

Primairy objective: To determine the diagnostic accuracy of MRI for the (differential) diagnosis of GB polyps and the differentiation between true and pseudo polyps in patients with suspected GB polyp(s) on previous imaging modality (TAUS) by using…

Understanding the Pathophysiology of metabolic dysfunction-associated steatotic liver disease and Metabolic Syndrome Following Cholecystectomy*

The aim of this study is to explore the biological and microbial alterations after cholecystectomy that contribute to the pathophysiology of metabolic syndrome and metabolic dysfunction-associated steatotic liver disease (MASLD).

Scrutinizing (in)efficient use of cholecystectomy: a randomized trial concerning variation in practice.

Current practice variation in selection of patients with gallbladder stones and abdominal complaints for cholecystectomy is not efficient. Here we evaluate stepwise selection for surgery to improve patient outcome and to reduce the number of…