685 results
The objective of this study is to investigate whether reconstruction of the radiocarpal joint by implantation of a tailor-made and patient specific 3D printed interpositional arthroplasty made out of Bionate® II 80A PCU (DSM®) is feasible as a…
Period 1: The first objective, of period 1, is to compare the safety and efficacy of ABT-494 15 mg QD monotherapy, and 30 mg QD monotherapy versus weekly methotrexate (MTX) monotherapy for the treatment of signs and symptoms of rheumatoid arthritis…
The aim of this study is to evaluate the long-term imaging and functional outcomes of overuse injuries of the wrist in (former) athletes.
A) To evaluate the use of real-time visual and audio feedback on the knee adduction moment and on kinematic patterns during gait in patients with knee osteoarthritis to decrease the biomechanical load on the knee via implicit learning and explicit…
to determine the percentage of patients with CKD, without a history of gout or attacks of arthritis, that have tophi measured by US,DECT and clinical examination. to determine the percentage of patients with CKD, that have tophi measured by US, and…
The aim of the current project is to evaluate the long-term effects of a) a pragmatic lifestyle intervention aimed at weight loss and b) a 30-month placebo-controlled intervention with glucosamine sulphate on the development of knee osteoarthritis…
Primary aim: Stepwise feasibility study to investigate whether intravenously administered macrophage tracers [11C]DPA-713, [18F]DPA-714 and/or [18F]PEG-folate accumulate in inflamed joints of rheumatoid arthritis patients using PET(-CT).Secondary…
To evaluate the safety, device-related complications, and performance of the NUsurface® meniscus implant as a device for the treatment of patients with degenerative and/or tears of the medial meniscus. .
The objective of this study is to evaluate the effectiveness and cost-effectiveness of surgical and conservative treatment of non-obstructive meniscal injuries in older patientsHypothesis: We assume equal improvement of physical function in both…
Feasibility of knee motion reproduction method for application in a hinged knee distraction device to apply reliable comfortable hinged knee joint distraction to be tested in future clinical studies.
The primary aim of the study is (i) to assess the effect of a soft brace on pain, knee stability and activity limitations. Secondary aims are (ii) to assess the difference in effect of two knee soft braces (i.e., non-tight and tight) on pain and…
The objective of this study is to evaluate the safety and technical feasibility of the Latella Implant in the treatment of patients with medial osteoarthritis of the knee.
To document the long term safety and efficacy of sarilumab added to DMARDs.
To assess the effects on knee pain, function, quality of life and change in structural features with respect to cartilage and subchondral bone of osteotomy surgery after one year of follow-up compared to the effects of treatment with an orthopaedic…
BoneMaster ITo perform a comparative assessment between the clinical, bone remodelling, and radiographic outcomes (as measured with RSA) of the conventional Hydroxyl-Apetite (HA) Taperloc stem compared with Taperloc stem with additional BoneMaster®…
To examine the effectiveness of an unsupervised e-health supported neuromuscular training program in combination with usual care in general practice compared to usual care alone in patients with acute lateral ankle sprains in general practice.
Primary: To evaluate the sustainability of subject benefits as quantified by the ASAS20 during long-term treatment.Secondary: ASAS40, safety and tolerability.
The objective of this project is to 1. increase accuracy and reproducibility of the most critical step in hip arthroplasty i.e. cup positioning;2. to alleviate one of the major complications of the straight lateral approach, i.e. abductor…
The primary objective of this study is to determine the rate of recovery of the ATTUNE knee from the time of surgery at the 6 month endpoint.
The main objective is to identify objective, neuromuscular and/or mechanic parameters through movement analysis, which are closely correlated to the subjective outcome of TKA. Secondary objective is to generate parameter specific hypotheses for our…