305 results
The primary objective is to assess neuropsychological function in X-ALD patients without active cerebral demyelinating disease. Data of minors will be compared to matched healthy controls. Data of adults will be compared to reference values. The…
The proposed study will further examine the effects of pregnancy on the human brain, by investigating structural and functional connectivity, local metabolite concentrations and neural activity related to social cognitive and memory processes.…
Investigating and comparing two disorders (i.e., OCD and GD) with phenomenological different types of compulsive behaviors central to their pathology can elucidate common mechanisms of compulsivity in psychiatry - core features- as well as specific…
Investigating the neural mechanisms underlying the anticipation of food reward induced by visual cues related to different foodcharacteristics in healthy males would provide 1) brain activity patterns that can be associated with the anticipation of…
The primary objective of the proposed study is to examine the neural substrate of cognitive and social-emotional apathy in patients with schizophrenia. Secondary, we intend to explore the concentration of brain metabolites and structural differences…
In this study we would like to investigate the effects of denervation on the cortical representation of finger articulations. We will assess the decodability of six different hand gestures from the American Manual Alphabet in people with an…
The aim of this study is to validate known, and identify novel allelic variants which may play a role in the risk of cisplatin-induced ototoxicity in a substantial international cohort of children diagnosed with cancer.
Main: To assess the effect of an early extra measles immunization between 6and 12 months of age on the development of humoral and cell-mediatedimmunity against measles following routine MMR immunization at 14months of age.Secundary:Determine effect…
Primary Objective: to investigate the role of the gut microbiota in RVV immune response Secondary Objectives: To investigate the role of the gut microbiota in tetanus and pneumococcal vaccine immune responses
1.Social CognitiveA.Do schizophrenia patients, compared to unaffected controls, show impaired social cognition (perceiving, understanding, intentions and emotions of others), especially when it comes to self-other distinction processes (…
The primary objective of this study is:to evaluate the effect of RPM + in-clinic follow-up versus in-clinic follow-up only on patient-reported health status/quality of life after implantation with an ICD/CRT-D device. The secondary objectives are: 1…
The primary objective is to study if quantitative (3- and 7-Tesla) MRI protocols (MRI perfusion, diffusion tensor imaging (DTI), and chemical shift imaging (CSI)) are able to detect phenotype conversion earlier than conventional MRI. Results will be…
1. Determine whether different classes of epigenetic modifiers affect HIV-1-specific T cell immunity.a. Investigate whether HIV-specific T cell exhaustion can be reversed by inhibitors of different classes of epigenetic modifiers.b. Examine whether…
Primary objective- Short- and mid-term repeatability of mDLS and LSCI measures;- Comparison of blood flow obtained by LSCI and blood flow obtained by mDLS;- Comparison of coagulation status obtained by mDLS and coagulation status assessed by…
The present study aims to identify processes underlying feedback related updating of stimulus-reward associations.
To assess the clinical and cost effectiveness of the anterior approach, compared to the conventional posterolateral approach for THA in terms of physical functioning and health-related quality of life
The current study investigates whether the ASPI-score is sensitive to context in which the ASPI is administered. Because the ASPI was designed to measure the capacity to experience sexual pleasure, it is expected that the ASPI score will not vary…
The primary objectives of this study is to investigate the modality-specific selective attention performance in older adults suffering from MCI.
Our interest is to gain a better understanding about cognitive complaints, mood and fatigue in relation to cognitive deficit in adults 30 to 60 years of age after a first cardiac event.
Primary Objectives The main objective of this project is to evaluate the long-term disease burden in meningioma patients. More specifically, we will evaluate: 1) the level of cognitive functioning and HRQoL in meningioma patients at least 5 years…