50 results
Primary objective: - What is the effect of the commercially available Water Flosser compared to interdental brushes evaluating gingival bleeding in a group of systemically healthy participants with gingivitis but without periodontitis?Secundary…
To study wether a biodressing impregnated with polyhexamethylene biguanide in the treatment of spoke injuries in children could give a reduction in pain during the treatment compared to the standard treatment with wound dressing impregnated with
The objective of the LEOPARD-2 trial is to assess the safety of MIPD versus OPD and after that to assess the time to functional recovery of MIPD versus OPD for symptomatic benign, premalignant or malignant peri-ampullary disease.
To investigate effectiveness of spinal chloroprocaine, and prilocaine in day case surgery. The null hypothesis is that there is no significant intergroup difference in complete recovery from motor blockade.
Primary Objective: To measure cortical spreading depression with full-band EEG during the migraine attack at patients aged 4 years or older. Secondary Objective(s): -To explore (additional) signal analysis techniques for detecting CSDs or infra slow…
The main objective is to compare the intramuscular carnitine status of pre-frail/frail elderly with fit elderly and young individuals. The secondary objectives are; 1) determine if intramuscular carnitine status is associated with carnitine levels…
The primary objectives are (1) to investigate the feasibility of online courses targeting nutrition and food-related behaviour and (2) to investigate whether the feasibility of the online courses is related to depressive symptoms. The secondary…
Primary Objective: The main objective is to investigate the effectiveness of PRT compared to CAU in school-aged children and adolescents with ASD.The primary research question is:1) Directly after treatment and at follow-up, what is the…
Objective: The aim of this study is to determine how joint coordination of children with DCD aged 5 to 11 years is affected compared to typically developing children when upper extremity movements are performed, i.e. reaching and interception…
Primary Objective: To study the effect of PNT and structured physiotherapy on function and pain of patients with lateral epicondylalgia.Secondary Objectives: To study the effect of PNT and structured physiotherapy on quality of life, patient…
Primary objective is to demonstrate a 25% reduction of the active irinotecan metabolite, SN38, in healthy liver tissue in patients with mCRC or other solid tumors as a result of preceding dietary restriction five days in advance. Secondary…
To evaluate the impact of electroencephalographic NarcotrendTM Index (NI) monitoring on the speed of emergence and recovery from PPS for PGE.
Primary objective:- To investigate if exercise can modulate neurogenesis and angiogenesis in vivo, and whether this is associated with changes in hippocampal function, such as pattern separationSecondary objectives:- To assess whether exercise-…
To demonstrate that the use of US-accelerated catheter-derived thrombolysis in patients with recently (less than 7 weeks) thrombosed infra-inguinal bypass grafts or native arteries with half the dose urokinase (50.000 IU/h) will significantly reduce…
To investigate whether a clinical medication review, focused on the perceived hindering complaints and personal wishes of the patients regarding their medication, improves health-related quality of life of older persons aged 70 years or older using…
To test the effectiveness of the optimized versions of an online alcohol moderation (AM) and smoking cessation intervention (SC) in samples of alcohol misusing or cigarette smoking cancer survivors, in comparison to control conditions (internet-…
To prolong the dysphagia-free period and to reduce the number of endoscopic dilations for patients with newly diagnosed, untreated benign anastomotic strictures after esophagectomy.
This study attempts to explore the relation between the functioning of the schema-related mPFC, REM sleep and affective memory bias, by simulating a depressive-like state in healthy subjects through negative mood induction and applying rTMS to…
The main objective of this study is to investigate which premedication scheme reduces best the pain during and after a BMAB and reduces best the fear for a possible next BMAB. Other objectives are the influence of the different medication schemes on…
We aim to determine the difference in uni- and bimanual coordination between young adults, older adults and MS patients. Additionally we want to determine the relation between the different measures of cortical inhibition and task performance.