453 results
Aim of the study is to determine the microvascular function in type 1 diabetes patients with concomitant celiac disease
Objective: Our main objective is to evaluate the additional effect of omega-3 fatty acids on maximal walking distance in patients with IC receiving SET. Our secondary objective is to evaluate the effect of omega-3 fatty acids on hemorheological…
The primary aim of this study is to investigate the recovery of the circadian rhythm of the hypothalamic-pituitary-adrenal axis during a glucocorticoid tapering regime. Secondary objectives include the effect of a tapering regime on melatonin rhythm…
1. Evaluate safety and clinical and angiographic efficacy of BTK revascularization with IN.PACT Amphirion* randomized to standard, uncoated PTA balloons2. Assess the clinical efficacy of BTK revascularization with IN.PACT Amphirion* compared to a…
Main objective of this pilot study is to investigate the placental bed histological phenotype and evaluate a scoring system for lesion characteristics of the placental bed spiral artery in pre-eclampsia and uncomplicated pregnancy. The secondary…
The primary objective is to compare initial PTA with supervised exercise therapy for patients with disabling intermittent claudication due to an iliac artery lesion in terms of mobility, functional status, health related quality of life and cost-…
The purpose of this study is to make it possible to make a prediction of risk of amputation stump wound healing without the need for re-intervention and whether a secondary amputation.
1. To assess the effect of the switch from protease inhibitors to raltegravir on endothelial function. 2. To assess the effect of the intervention mentioned above on markers of endothelial function; immune activation; chronic inflammation; and, on…
The aim of this study is to evaluate whether adding edoxaban to aspirin following femoropoplitealendovascular intervention will enable maintenance of vessel patency and prevent restenosisrelative to current treatment with clopidogrel and aspirin.
The primary objective is to assess the difference in absence of binary restenosis rate of endovascular treatment of intermediate and long lesions of the superficial femoral artery with the Legflow® PEB and nitinol stent, when compared to uncoated…
To assess the long-term consequences of live kidney donation, regarding kidney function, survival, hypertension, diabetes, systolic and diastolic blood pressure, mental state and quality of life.
To compare the blood pressure lowering effect of thiazides against calcium channel blockers in CNI-induced hypertension.
To gain a better insight into the genetic factors that play a role in the etiology of the thoracic aortic aneurysm with the following specific aims:1. Study of specific geneitc factos that play a role in the pathogenesis of both syndromic and non-…
Primary research questions To investigate whether the outcome after the randomized implantation of the Resolute Integrity® versus Promus Element® drug-eluting stent are similar, as assessed in a non-inferiority setting by comparing target-vessel…
The general aim of this study is to implement validated markers for CAA in asymptomatic individuals with CMBs, to investigate whether presence of CMBs signifies early CAA.
Our study tries to identify the ideal sclerosant dosage for the ClariVein® system in order to occlude the GSV permanently. By choosing the lowest dose with the same anatomical success rate, we achieve a safe treatment which also gives us the…
To determine the difference in EGG patterns in a fasting state and after a test meal between healthy controls and patients suffering from splanchnic ischemia (both single and multiple vessel stenosis). We hypothesize that patients with splanchnic…
The primary objective of this study is to determine whether the Impella cVAD device vs. IABP therapy leads to a higher 30 day survival rate in shock STEMI patients in the setting of primary PCI.
The main object is to evaluate the validity of a diagnostic screening package for bleeding tendency consisting of point-of-care devices when compared with the gold standard for bleeding tendency diagnosis.Other objects which will be investigated are…
To study the effects of flaxseed oil, rich in ALA on 24h-ambulatory mean arterial pressure (MAP) in men and women with high-normal blood pressure and mild hypertension compared to high oleic sunflower oil, poor in ALA.