40 results
The main point of this study is to detect in a controlled fashion if there is a relationship between CCSVI and MS. We focus on 5 parameters indicative of CCSVI: 1-reflux in the internal jugular vein (IJV) or in the vertebral vein (VV), or both with…
The primary goals of this study are to: i. Identify genetic variations responsible for PLP across the whole genomeMore than 90% of SNPs are found in introns or intergenic regions and most of them are probably of little functional consequence.…
To gain further insight into the interaction and possibly shared pathophysiological mechanisms of female-specific cardiovascular risk factors and events we will quantify white matter hyperintensities on brain MRI and assess endothelial function in…
The aim of Prevent CardioKids is to evaluate to what extend disturbed vascular function markers are present in children of different weight categories and whether these are age dependent. Also differences * and relationships between * vascular…
1. Validate and adjust the current classification criteria for systemic vasculitis2. Develop and validate new diagnostic criteria for systemic vasculitis
To develop pulse transit time into a diagnostic device which can be used to assess an altered cold/heat mediated vasomotor response (CHMV) (central component) and the flow-mediated dilatation (FMD) (peripheral component) in CRPS patients.
The aim of this study is to compare the 16S PCR technique with standard bacterial cultures of infected vascular grafts, mycotic aneurysms and non-infected aortic aneurysms.
To describe the differences in macrophage infiltration and mRNA expression of adipocytokines in subcutaneous, omental and perirenal fat tissue in Cushing's syndrome compared to healthy controls.
Measuring the thickness of the microvascular glycocalyx, and make a comparement between lacunar stroke patients and healthy controls.We also compare glycocalyx between patients with and without concomitant silent signs of cSVD on brain MRI.
To assess the feasibility of measuring a course in ischemia and endothelial activation in antecubital venous blood during cooling and recovery in patients Raynaud*s phenomenon, primary and secondary to SSc with and without Pulmonary Arterial…
To determine the vaginal microbiota composition during preeclampsia
The combination of simvastatin 10 mg/ezetimibe 10 mg has a beneficial effect on post prandial endothelial function in comparison to monotherapy with simvastatin 80 mg.
This study concerns a research that is aimed to investigate the prevalence of the metabolic syndrome in a group of patients known with ANCA-associated vaculitis. Hereby we will compare the presence of the metabolic syndrome between an ANCA-…
The objective of this pilot study is to provide information about the usefulness of NIRS in the study of patients with JDM in the test configuration as described in the protocol. For this purpose, the microvascular oxygenation and hemodynamics in…
To show the differrence of total healing of wound between two therapies, VAC and gauze-therapy, in patient with a sinu pilonidalis after chirgical intervention.
Primary objectives1. To investigate prospectively the prevalence of cardiovascular damage due to cancer treatment and it*s change over time.2. To investigate markers of early and late toxicity of cardiovascular damage due to cardiotoxic treatment.…
Aim of the study is to determine the microvascular function in type 1 diabetes patients with concomitant celiac disease
The primary aim of this study is to investigate the recovery of the circadian rhythm of the hypothalamic-pituitary-adrenal axis during a glucocorticoid tapering regime. Secondary objectives include the effect of a tapering regime on melatonin rhythm…
1. To identify presymptomatic and symptomatic profiles including (early) disease stages and early biomarkers of disease progression and to elucidate pathophysiological mechanisms, we will investigate RVCL patients at different ages (both symptomatic…
The main aim of the study is therefore to examine mu wave activity during observation, execution of movements and during movement imagery in comparison to a passive resting state and active relaxation condition in stroke patients and matched healthy…