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Does have autologous blood withdrawal pre-operative with and without sequestration, effect on the usage of allogeneic bloodproducts during and after heartsurgery.

When it is possible to prove that there is a significant difference between the sequestration group and the other two groups, it also will be possible for patients with a smaller body surface to donate autologous blood and also this group will need…

Do washed irradiated red blood cells with a balanced solution improve the quality of the priming in cardiopulmonary bypass for neonates and infants?

Improve the quality of red blood cells used for cardiopulmonary bypass for neonates and infants with a bodyweight smaller then 10 Kg.

Catheter ablation versus Amiodarone to prevent future shock episodes in patients with a defibrillator and a history of a myocardial infarction.

The main objective of this study is to compare the occurrence of next ICD shock therapy for VT or VF in patients with hospital presentation for an ICD shock therapy for VT or VF, with a history of a myocardial infarction, between patients randomized…

The Cardio Thoracic Harness

The objective of this study is to get insight in the effect of the Cardio Thoracic Harness for men and the Cardio thoracic bra for women. The harness and the bra possibly have an important role in pain management. The producer of the harness and the…

The effect of two different heart-lung machines, Twin-Pulse Life Support and standard used heart-lung machine, on the systemic inflammation and pattern of microvascular blood flow. A prospective randomised clinical trial.

Analysis of the effects of the Twin-Pulse Life Support on on the systemic inflammatory response and the effect on microvascular blood flow in ocmparison to standard used Extracorporeal Circuit Device

Comparison of Biolimus Eluted from a Erodable Stent Coating with Bare-metal Stents in Acute ST-elevation Myocardial Infarction & In Vivo 3-Vessel Assessment of Time-Related Changes of Culprit and Non-Culprit Lessions by Grayscale IVUS, IVUS-VH and OCT in Acute Myocardial Infarction.

To establish superiority of the biolimus-eluting (BiomatrixTM) stent compared with an otherwise identical bare-metal stent (GazelleTM) in acute ST-segment elevation myocardial infarction (STEMI) in terms of the composite endpoint of cardiac death,…

The Real-World Endeavor Resolute versus Xience V Drug-Eluting Stent Study in Twente

Primary research questions:* To investigate whether the clinical outcome following the randomized implantation of the Endeavor Resolute® versus XIENCE V® drug-eluting stent is similar, as assessed in a non-inferiority setting by comparing target-…

Preserved platelet function during cardiopulmonary bypass with aprotinin in dual antiplatelet therapy.

Primary objectiveTo determine whether aprotinin can reverse the increased postoperative blood loss, induced by dual anti-platelet therapy in elective non-complex cardiac surgery.Secondary objectiveTo determine whether aprotinin reduces transfusion…

Optimization of prime fluid strategy to preserve microcirculatory perfusion during cardiac surgery with cardiopulmonary bypass

- Part I: determine the difference in microcirculatory perfusion between three different prime fluid strategies in patients undergoing elective cardiac surgery with cardiopulmonary bypass.- Part II: To determine the effect of limiting hemodilution…

A randomized clinical trial to study positive effects of "T-REX Twente regimen" (Thoracic surgery Rehabilitation Experts Twente) on quality of life and mobilisation activities for cardiac surgery patients after full median sternotomy, compared to usual care

Do the T-REX Twente precautions have a positive impact on the quality of life (MAcNew QLMI), level of physical activity, and reduction of fear of movement in heart patients after a total median sternotomy compared to the (current) standard…

High intensity interval training in patients with a right ventricle to pulmonary artery conduit

Primary Objective: To assess the efficacy, expressed by change in peak oxygen consumption obtained with cardiopulmonary exercise testing (CPET), of a HIIT program in patients with an RV-PA conduit.Secondary Objective(s): To determine predictors for…

Antiplatelet therapy for patients undergoing transcatheter aortic valve implantation

1. To investigate the safety of omission of clopidogrel compared to a strategy using aspirin + clopidogrel during 1 year follow-up in patients without an indication for OAC after TAVI (Cohort A);2. To investigate the safety of omission of…