15 results
To determine whether the attenuated salivary cortisol response in children with asthma can be explained by the maintenance use of inhaled cortiocosteroids, the chronic inflammatory disease, or the attenuated exercise capacity.
The aim of this study is to determine whether children between 5-17 years born to women with an autoimmune disorder and prednisone use during pregnancy have chronically elevated cortisol levels compared to children born to women with an autoimmune…
To determine the sensitivity and specificity of salivary metanephrines and in patients with PCC/sPGL.
Objectives: Part 1) To assess the prevalence of PA in general practice (part 1 of this study);Part 2) To describe differences of cardiorenovascular damage in newly diagnosed hypertensive patients with versus without PA (part 2 of this study);Part 3…
The primary aim of this study is to investigate the recovery of the circadian rhythm of the hypothalamic-pituitary-adrenal axis during a glucocorticoid tapering regime. Secondary objectives include the effect of a tapering regime on melatonin rhythm…
To determine the value of multimodality image registration of cone-beam CT (CBCT) and CT in increasing the success rate of adrenal vein sampling procedure compared to procedures without CBCT guidance.
Primary objective:to identify new and improved disease biomarkers and establish the biochemical and molecular basis for variations in the clinical presentation of the different groups of tumors.Secondary objectives:• compare the diagnostic utility…
To answer the following research questions:How is quality of life in patients with adrenal insufficiency?How is cognitive functioning in patients with adrenal insufficiency?Is there a difference in cognitive functioning between patients who did/did…
Study the mechanisms of BAT activity and the effects of BAT acitivity on energy homeostasis.
To study HPA axis regulation and sympathetic nervous system activity in survivors of childhood ALL during relaxation and during stress.
Assess the prevalence of the metabolic syndrome and quality of life in patients with Addison*s disease treated with low dose GRT. Study the relation between GRT, QoL and glucocorticoid receptor polymorphisms
The aim of the present study is to assess the necessity of dietary restrictions before sampling for the biochemical diagnosis of pheochromocytoma. Therefore, the short-term influence of a catecholamine-rich diet on plasma free and total metanephrine…
To detect differences between ACC patients and controls without ACC, and between the diseased and healthy adrenal gland of ACC patients, in microRNA (miRNA), circulating cell-free tumor DNA (ctDNA), circulating tumor cells (CTCs), and steroid…
To study the effects of 2 standard treatment timing strategies for glucocorticoid dosage on androgen concentration in CAH children: a. highest dosage in the morning, b. highest dosage in the evening.
The purpose of this research study is to compare the safety and effectiveness of Chronocort® with current glucocorticoid treatment regimens in the treatment of CAH over a 6 month period.