14 results
To characterize the interaction between the gut microbiome, related metabolites, immune function, and perceived complaints in QFS-patients, CFS-patients, and healthy individuals.
The aim of this study is to explore the prevalence of HAND in people living with HIV.
The aim of this study is to create a prognostic model enabling the clinician to predict the outcome of a septic episode. Furthermore, by getting more insight in the pathophysiologic proces of sepsis, we could discover new possible targets for future…
The aim of the study is to explore the prevalence of HAND in people living with hiv.
Primary Objective: To study stimulating effects of prolonged (8h) enteral L-citrulline supplementation on the normalisation of the Arginine-NO metabolism.Secondary Objective: To study stimulating effects of prolonged (8h) enteral L-citrulline…
To evaluate the effect of age of transfused erythrocytes on expression of *eat me* signals on erythrocytes in several critically ill patient populations (septic and non-septic patients) and to correlate these signals with parameters of impaired…
To study the relationship between (a) abnormal concentrations of plasma amino-acids, pterins, HVA and inflammatory parameters and (b) the severity, duration and outcome of delirium. To find a biochemical profile that predicts the occurrence of a…
Objective of this study is to provide evidence for the induction of AGEs in blood and tissue in patients with septic shock.
In this project, we aim to study how local and systemic antibody by distinct B- and T-cell populations control periodontal health, in particular control the conversion of gingivitis into destructive periodontitis. Which types of B cell responses are…
This study will investigate the value of C. burnetii-specific whole-blood IFNγ and IL-2 production assays in QFS patients that have either recovered, or are still substantially fatigued. This will show us if these assays can serve as potential…
This study will try to objectify if C. Burnetii is able to induce epigenetic changes in monocytes and macrophages, ultimately resulting in a changed cytokine profile. Subsequently, this study will try to link these epigenetic changes to mRNA…
We aim to find immune defects and related genetic variants in patients who have recovered from secondary HLH
Achieving more detailed information about the possible auto-immune process that underlies narcolepsy by:(1) Assessing differences in immune composition between peripheral blood samples of healthy controls (n=30) and type 1 narcolepsy patients (n=30…
First objectives To assess the influence of apical periodontitis on the peripheral blood-plasma concentration of inflammatory mediators and to investigate the metagenome of root canal infections. Other objectives: To search for clusters and patterns…