36 results
To assess the cost-effectiveness and cost-utility of at-home foot temperature monitoring to reduce incidence of foot ulcer recurrence in patients with diabetes. Main research questions:1. What is the cost-effectiveness of enhanced therapy in…
In this study, the following questions will be answered:1. Does larval therapy accelerate wound healing?2. Do single larval secretions accelerate wound healing?3. Is the bacterial load in the wound reduced during larval therapy or is the microbiome…
The primary objective of this study is to assess the efficacy of the use of motivational interviewing to improve adherence to wearing prescribed footwear in diabetic foot patients. Secondary objectives are to assess the feasibility of applying…
The objective of the study is to gain insight in the role of endogenous GLP-1 on food-stimuli related CNS satiety and reward responses and the alterations between lean and obese-T2DM individuals. Also, to gain information about treatment with a GLP-…
Primary Objective: To assess immediate and long-term effects of Mindfulness-based Cognitive Therapy (MBCT) and Cognitive Behavioral Therapy (CBT) in reducing depressive symptoms in patients with diabetes. Regarding immediate effects, we expect that…
We propose a 2-week randomized controlled, single-blinded pilot study to compare the health effects of a Paleolithic diet and an isocaloric reference diet (based on the *Guidelines for a healthy diet 2006*) on markers of the MetS which are risk…
The primary objective of this study is to evaluate tolerance of a new high-energy high-protein oral nutritional supplement compared to a commercially available high-energy high-protein oral nutritional supplement in elderly subjects in need of oral…
To investigate the potential beneficial effect of increasing protein in the diet in order to decrease hepatic lipid accumulation on a high-fat diet.
To characterize the glycaemic and insulinaemic responses of regular camel milk and camel milk powder in healthy adults.
The objective of the first part of the study is to assess whether circadian misalignment: - decreases energy expenditure and activity induced energy expenditure - alters substrate oxidation- alters feelings of hunger and satiety - alters food choice…
1. Measurement of the 24-hour glycemic profile in response to acute submaximal hypoxic and hyperoxic exercise in order to determine its effectiveness and select the most efficient method in reducing post-exercise hyperglycemia prevalence in…
The objective of this study is to investigate the effect of broccoli seedlings on postprandial inflammatory parameters and insulin sensitivity after an oral glucose load (dual isotope technique) and monitoring the bioavailability and kinetics of SFN…
To investigate whether single dosis of fecal therapy by infusion of allogeneic (post bariatric surgery donor feces in the bowel) or autologous (own feces) have differential effect on lipid-metabolism-mediated insulin resistance.
The aim of the current proposal is to compare the (cost)effectiveness of a 12-month multidimensional lifestyle approach for SMI outpatients to usual care to reduce cardiometabolic risk factors in SMI patients. Secondary research questions include…
To determine differences in food cue reactivity between lean individuals and individuals with overweight. We will study behavioural (food choice, food intake, mood ratings) as well as physiological parameters (heart rate, skin conductance, saliva…
Objective: The primary objective is to evaluate whether distal LRYGB (DLRYGB) is superior in terms of %EWL after one year follow-up compared to standard LRYGB (LRYGB). Secondary objectives are to evaluate effect on quality-of-life (QOL), cure /…
In this RCT we combine cognitive behavioural therapy (CBT) with a maintenance contract and a specific diet (very low calorie diet), to obtain and maintain favourable effects on weight and risk profile over the long term.
Do high plasma free fatty acids lower central serotonergic responsivity?
However, prior to further implementation of this programme, insight into the effectiveness is needed.Specifically, what is the effectiveness of a targeted prevention programme with regard to the prevention of DM and *in the long-term- DM-related…
Objective of the study:1) To assess insulin sensitivity and response in critically ill septic neonates and children.2) To determine protein balance in septic, critically ill children at baseline and during a HyperinsulinemicEuglycemic Clamp, while…