Search for a trial

RCT comparing insertion of levonorgestrel releasing intrauterine system (Mirena) during the menstruation compared with random insertion beyond menstruations in patient-perceived pain.

In this randomized study, timing during (day 1-7 of the menstruation cycle WITH vaginal blood loss) or beyond menstruation (in menstruation cycle day 8 and further WITHOUT vaginal blood loss) will be compared regarding differences in patient-…

Systemic fibrinolysis in women with menorrhagia

Main: Investigate the cyclic variation in clot lysis time in women with HMB in comparison to controls. Secondary:- Investigate the cyclic variation in TAFI, PAI-1, tPA, PI, thrombin generation, fibrinogen, fibrin clot permeability and confocal…

RCT comparing the levonorgestrel releasing intrauterine system (Mirena) versus endometrial ablation in women suffering from menorrhagia

We plan to compare the costs and effects of both methods.

A Single-Dose, Open-Label, Randomized, 2-Way Crossover Pivotal Study to Assess the Bioequivalence of NGM/EE Tablets Manufactured at 2 Different Facilities

- To establish the bioequivalence of the hormones norgestimate, norelgestromin, and ethinyl estradiol in NGM/EE Schaffhausen tablets compared with the same hormones in NGM/EE Manati tablets.- To assess the safety and tolerability of both…

Scar Evaluation after Caesarean by Ultrasound Registry

Ultrasonography shows a niche at the site of the uterine caesarean scar in the majority of women with a CS in the past history. A niche is a triangular, anechoic area at the presumed site of incision. Our primary objective is to develop an…

A randomized, parallel-group, multicenter study to assess the efficacy and safety of vilaprisan in subjects with uterine fibroids

The primary objective of this study is to assess the efficacy and safety of vilaprisan in subjects with uterine fibroids compared to ulipristal. The secondary objective of this study is to evaluate the efficacy and safety of different treatment…

NATURAL KILLER CELL RECEPTOR VARIABILITY DURING THE MENSTRUAL CYCLE

The main goal of this study is to analyse the influence of the menstrual cycle on NK cell receptor variability.

Procedural sedation for hysteroscopic myomectomy: cost effectiveness

Is hysteroscopic resection of submucous myomas under procedural sedation with propofol (PSA) in an outpatient setting a cost-effective alternative for hysteroscopic myomectomy performed under general anesthesia in the operation room?

Diagnosing endometriosis using exhaled breath analysis by Electronic Nose: a pilot study

The aim of this pilot study is to determine the diagnostic value of exhaled breath analysis by eNose technology for endometriosis patients: does it detect endometriosis?

SAFE: Sequre for Adenomyosis and Fibroid Embolisation

The aim of this research is to test the efficacy and safety of a new microcatheter 2.8F Sequre for treatment of uterine fibroids and/or adenomyosis with a standard embolization technique and to demonstrate the added value of this catheter, namely to…

How 2 deal with PCOS

To study if an online brief CBT intervention is effective for anxiety and depression compared to care as usual (CAU) in patients with PCOS

Symptomatic niches for laparoscopic niche resection, a randomized clinical trial

Set up an RCT to study whether a laparoscopic niche resection is superior over hormonal therapy as treatment of niche-related gynaecological complaints for women with a large symptomatic niche, and without a child wish.

A randomised controlled trial comparing endometrial ablation plus levonorgestrel releasing intrauterine system versus endometrial ablation alone in women with heavy menstrual bleeding (MIRA 2 trial).

To determine whether the introduction of a levonorgestrel-releasing intrauterine system (LNG-IUS) directly after endometrial ablation (EA) alleviates pain and heavy menstrual bleeding and reduces the need for subsequent hysterectomy compared with…