819 results
Primary Objective: 1. Test whether the flash lag illusion is decreased in PD and more specifically whether the decrease is associated with bradykinesia.Secondary Objective(s): 2. Quantify bradykinesia by means of motion sensors and validate this…
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The primary objective is to establish the effect of a unilateral task performed with the non-paretic arm on dynamic joint admittance and reflex gain of the wrist of the paretic arm in stroke patients compared to the effect of a unilateral task on…
To investigate whether it is possible to induce epileptiform activity with TMS. We expect to see abnormal discharges on TMS-EEG and we expect that these findings are of diagnostic value and will help to localize the epilepsy.
The main objective is to examine the effectiveness, the costs and the cost-effectiveness of an integrated *fast track* rehabilitation service for multi-trauma patients (SFTRS) involving dedicated early rehab intervention programs. The SFTRS is…
Our goal is to develop and validate a Movement Diagnostic System (MDS) to accurately locate specific CNS pathological changes in ET, PD-T and DYS, with the use of fMRI and scanner compatible EMG, accelerometry, video, and wrist perturbator.
The primary objective is to study the effects of 12 weeks of treadmill training with virtual reality on neural plasticity in comparison to the effects of treadmill training without virtual reality.Secondary objectives are to investigate the role of…
The aim of this study is to investigate the effectiveness of the Phystrac in people with Carpal Tunnel Syndrome.The primary research question is:- Is there evidence that Phystrac might be an additional non-invasive option of treating CTS patients…
The objective of this study is to investigate whether impaired balance control is (partly) responsible for the increased energy cost of walking in stroke patients and amputees by evaluating the effect of external stabilization and destabilization on…
The main, primary objective of this study is identification of the molecular mechanisms that regulate structure and function of red blood cells in patients with neurodegeneration accompanied by the presence of abnormal red blood cells (…
The main objective of this study is to compare DTI findings of PPS patients with those of healthy controls. Secondary objective of this study is to correlate DTI findings with clinical data such as isometric muscle strength. Third objective is to…
In recent years, we have identified a Dutch family and performed a large number of studies which have helped us gain insight into the disorder. (MEC protocols 02/223 and 03/140, Dissertation Van Rootselaar, 2006). We want to call on family members…
As none of the proposed experimental conditions have been executed with chronic pain patients, our main objective is to determine the sensitivity of the experimental conditions. Besides, we investigate the attention-bias for pain signals that…
The objective of this study is to provide a reliable overview of the oral health of Parkinson's disease patients in the Netherlands.
First, we investigate the attention-bias for pain signals that chronic pain patients (CPP) are suggested to have. Second, we investigate whether the chronicity of pain is related to faster learning and slower *unlearning* of new associations between…
The main objective of our research is to develop an FCE for use in one-handed individuals. The main objective of this part of the study is to gain descriptive data on muscle tension of the back, neck and shoulder, joint movements of the shoulder,…
The main goal of this study is to investigate the influence of STN DBS on the cognitive processes of reward processing and selective visual attention.
The objective of our study is to investigate the relationship between electrical stimulation of the central nervous system (VNS) and reward-based selective attention. In order to do so, we will ask subjects to complete a set of tasks on a standard…
Primary Objective: To examine which subregions of the hippocampal formation on 7 Tesla MRI are most affected in patients with early Alzheimer*s disease compared with older persons with normal cognition. Secondary Objectives:a) To explore risk…
Primary objective: To evaluate change in RNFL thickness in RRMS patients followed for up to 36 monthscompared to a group of reference subjects (without neurologic or ophthalmic disease) todetermine whether the technology is sufficiently sensitive to…