819 results
To investigate whether balance control is asymmetrical in PD patients. In addition, we want to investigate the relationship between asymmetrical balance control and stepping responses, fall history and freezing of gait.
This project has three separate but complementary research objectives. First, to find out whether there is indeed evidence of subclinical cerebellar dysfunction in these subjects, by specifically focusing on cerebellar motor learning. Second, to…
The first objective of this study is to assess whether emotional responsiveness in PD patients is different from that of matched healthy controls and whether emotional responsiveness in PD patients with apathy is different from that in PD patients…
The aim of this study is to determine whether the hydration status influences the RNFL thickness.
There is a complex organization in the motor system that channels the spatiotemporal commands necessary for a writing task and surround inhibition is a physiological mechanism to focus this neural activity. Surround inhibition (SI) aids the…
The aim of the present study is to increase the understanding of the optimal administration of mirror therapy and thereby improve the quality and effectiveness on this therapy. In order to realise this several different applications of mirror…
We propose an instrumented approach, during which the ankle is rotated in a precise and controlled way using a robot manipulator. Using neuromuscular modelling, key neuromechanical parameters as viscosity, stiffness and reflexive torque can be…
We hypothesize that intracranial vessel wall atheromas are an important underlying cause of middle cerebral artery obstruction. To test our hypothesis we will perform high resolution intracranial vessel wall imaging with a 7.0 Tesla MRI scanner in…
To determine whether Wii balance therapy is more effective than the conventional balance therapy for the standing and walking balance of patients with a stroke.
1) To investigate the VDR levels in different MS associated T cell subsets2) to compare the VDR levels in the different T cell subsets between MS patients and age and gender matched healthy volunteers
Primary researchquestion:1. What are the differences in eye-hand coordination in patients with left or right hemisphere damage compared to healthy age-matched controls?Secondary research questions:2. What is the difference in eye-hand coordination…
The goal of PCI is to increase the neurological disease-free survival, without significant side effects, and hence to improve HRQOL. This sub-study aims to investigate this expected advantage of PCI in NSCLC in maintaining function and increasing…
Main objective: Contributing to the debate on the necessity of PPC in episodic memory by support of patient data. Secondary objective: Exploring the episodic memory theorem and developing a more sensitive (neuropsychological) research tool usable in…
-
The objective of this study is to test the hypothesis that in patients with inflammatory neuropathies and conduction blocks, corticosteroid treatment leads to:1. Hyperpolarization and reduced excitability of motor axons. 2. An increase of the number…
The purpose of this study is to gain insight into the effects of auditory pacing on the stability and flexibility of hemiplegic gait coordination. It will be examined how auditory pacing can be best administered to improve the quality of hemiplegic…
To investigate whether exposure to nanoparticles is able to induce short-term functional changes in the brain, we previously exposed human volunteers for one hour to diesel exhaust particulates (300 ug/m3) and followed their brain activity during…
Primary: To determine whether medical management improves long-term outcomes of patients with unruptured BAVMs compared to invasive therapy (with endovascular procedures, neurosurgery, or radiotherapy, alone or in ombination). The trial has been…
The main research question of this study is:Is client-centred occupational therapy according to the Occupational Performance Process Model more effective than usual-care occuaptional therapy in patients with multiple sclerosis?
To assess whether there is less peri-operative pain and a faster post operative recovery.