819 results
Is the muscle weakness during cataplexy due to pre- or postsynaptic inhibition? In other words: what happens with the H-reflex and Magnetic Evoked Potential during REM sleep and cataplexy?
The current study further investigates residual vision in hemianopics by using a new measure of distractor interference on saccadic eye movements. Previous research with healthy participants has indicated that irrelevant distractors evoke saccade…
Objective: to determine whether botulinum toxin A (btA) injections, intensive bimanual skill training, or a combination of both leads to more and better use of the affected arm in hemiparetic children in play, leisure time, school and personal care.
To construct an optimal diagnostic protocol enabling general practitioners to distinguish between dizzy elderly patients who need treatment, dizzy elderly patients who need further diagnostics and dizzy elderly patients who need no further…
The primary objective of this study is to evaluate the impact of carbon dioxide field flooding on the quantitative intraoperative microembolic load of the brain during aortic arch surgery.A secondary objective is to evaluate any concomitant…
To evelauate whether the presence of selected polymorphisms has an effect on the response to lamotrigine.
The objective of this study is to prove patients with CTTH and chronic neck pain after a whiplash injury have a lower nociceptive flexion reflex threshold compared to painfree controls.
To identify neurophysiological mechanisms (e.g. synchronisation / desynchronisation) and brain areas (i.e. localization) involved in the performance of cued movements in PD.
The development of an attractive child centred intervention based on the forced use perspective, to study the effects regarding the following question:Is a period of 6 weeks Forced Use of the more affected upper limb (I) for children with Cerebral…
The aims of the study are fourfold: 1) to assess dual-task walking performance in patients with late sequelae of polio and compare this to dual-task walking performance of age-matched healthy controls; 2) to investigate the reproducibility of a dual…
Zonisamide (Zonegran) and sodium valproate (Epilim) are both medicines approved for the treatment of epilepsy. This study is intended to investigate to what extent zonisamide can affect your memory and concentration in comparison with sodium…
Objectives1. Achieve a complete ascertainment of incident CIAP patients in the middle of the Netherlands during a three-year period and determine the frequency of CIAP.2. Establish whether CIAP is associated with the metabolic syndrome, and if so,…
1. To investigate the prevalence of an absent R1 component in migraine patients compared with healthy controls.2. Do headache characteristics differ between migraine patients with a R1 response and those without a R1 response ( Fast progressing vs…
Further investigate the energy cost for balance control in patients after stroke and to compare the energy costs of stroke patients and healthy controls during quiet standing with and without balance perturbations. The energy costs will be related…
The objective of this study is the visualisation of diffuse and focal lesion in the brain in Multiple Sclerosis on higher main magnetic fields. Images from 1.5 Tesla MR scanners will be compared with images acquired at 3 Tesla and images made on 3…
To assess if the studied TCD variables of cerebral autoregulation and hemodynamics are abnormal during preeclampsia. And if so, to determine if these changes are large enough to have potential value to determine a threatening cerebral dysfunction in…
The main objective of the study is to acquire more insight in memory for emotional information in patients with Alzheimer*s Disease, compared to healthy elderly people. A second objective is to explore the effect of emotional content on working…
To evaluate a group treatment program to stimulate effective coping with chronic neuropathic pain following spinal cord injury.
The two objectives of our proposal are: (i) to identify specific gene expression profiles in blood and fibroblasts from patients with ALS or ALS-mimic in order to improve diagnosis and measure disease progression; (ii) the identification of genetic…
To investigate if:-Kiovig is at least as effective as Gammagard. (equivalence)-Kiovig has a good side effect profile for CIDP patients.-Whether patients prefer Kiovig to Gammagard.