729 results
1. A safe and effective treatment protocol for the Vacoped is: Application of the Vacoped in the operating theatre/emergency department, with partial load-bearing up to 20 kg allowed from day 2. Full load bearing is allowed from day 10-14, with a…
We hypothesize that endoscopic ultrasound-guided celiac ganglia neurolysis (EUS-CGN) is more effective in achieving adequate pain reduction in malignant upper-abdominal pain or back pain than percutaneous splanchnic nerve neurolysis (P-SNN)
It is hypothesized that both surgical techniques do not make more than 10 points difference in the American Orthopaedic Foot and Ankle Society (AOFAS) lesser toe metatarsophalangeal scale, one year after surgery.
The combination of cisplatin-pemetrexed-erlotinib is superior to standard of care erlotinib monotherapy as first line treatment in prolonging progression free survival in patients with advanced NSCLC whose tumors harbor an EGFR mutation.
In this randomized study, reduction of incidence and intensity of postlaparoscopic pain will be estimated by using a combination of two therapies, intraperitoneal normal saline and the pulmonary recruitment maneuver.
The effect of EMDR in adults with autism has not been studied before. Hypothesis is that the severity of traumarelated symptoms decreases after treatment with 8 sessions EMDR in comparison of treatment as usual. There are indications of diagnostic…
We hypothesise that a primary care-based multifaceted intervention aimed at optimising pain management will provide benefit over ‘care as usual’ in children with acute otitis media (AOM).
The HF IF PIOL can safely and effectively correct myopia in patients with low to high myopia and who have otherwise healthy eyes.
An unsupervised e-health supported neuromuscular training program, in addition to usual care in general practice, is more effective compared to usual care alone as a treatment for patients with acute lateral ankle sprains in general practice.
Preoperative pain treatment by means of duloxetine will improve postoperative outcome after total hip or knee arthroplasty by reducing residual pain
The hypothesis is that modarate and late preterm infants at age 12 reported more symptoms consistent with asthma and use more asthma medications, as well as a poorer lung function, exercise capacity and Lung Clearance Index than healthy peers.
The effectiveness of the commercial video game Journey in preventing depression will be tested in a Dutch sample of adolescents with elevated depressive symptoms. In an RCT design the effectiveness of Journey will be compared to the effectiveness to…
Assess the safety and tolerability of single ascending Intravenous (IV) infusion doses of ABP-700
Ten weeks of daily dual-channel functional electrical stimulation assisted gait training starting in the sub-acute phase after stroke is feasible and enhances gait efficiency compared to conventional gait training.
We expect youth in the intervention group to show greater improvements in change beliefs, empowerment, coping and self-worth and greater reductions internalizing and externalizing problems in comparison to youth in the control group.
The objective of this pilot study is to determine the feasibility of a larger non-inferiority trial investigating the safety of tacrolimus monotherapy (TACmono) in terms of rejection rate after kidney transplantation. Feasibility objectives are…
We hypothesize that the Vanguard TKA show similar and comparable outcome measures and survival as the Maxim TKA
In patients with previous adequate quality of VKA therapy, VKA therapy is superior to NOAC therapy, in terms of net clinical benefit as well as cost-effectiveness
Patients treated with MIS will document lower back pain scores on VAS at the short-term follow-up (first 6 weeks after surgery) as compared to open surgery.
The medication review is a well-structured pharmaceutical care service, developed to optimize pharmaceutical care for patients with polypharmacy. Patient reported outcome measurements (PROMs) aim to measure the outcome for patients. Implementation…