55 results
The aim of this study is to investigate the effectiveness of EMDR with traumatized adolescents (12-18 years) with major depressive disorder.
To evaluate the additional effect of coal tar treatment to a corticosteroid regimen in adults (aged >16 years of age) with moderate to severe atopic dermatitis, based on the percentage change in Eczema Area and Severity Index (EASI) at week 2…
The purpose of this investigation is to evaluate decellularized homograft for aortic valve replacement (ARISE AV) rates in comparison to current valve substitutes within a large prospective multicentre surveillance at 6 leading European Centres for…
Study I aims to explore dysregulation of biological stress systems among traumatized youths with and without ID in residential care, and compare them with a healthy control group. Study II aims to conduct a randomized controlled trial (RCT) to test…
Here we will generate iPS cells from patients with genetic neurodevelopmental disorders and (related) healthy control individuals, that can be used to generate in vitro disease models to further study the mechanisms behind these disorders.
Get insight in the implementation and effectiveness of the integrated preventive care chain for overweight children in 's-Hertogenbosch. With the results we can optimize the support for overweight children and their parents. .
To contrast jaw exercises and corticosteroid injection via arthrocentesis in children with JIA and MRI confirmed TMJ arthritis despite 1 year regular treatment by the rheumatologist, in a randomized clinical trial, both in combination with continued…
Hypothesis: Early life stress is associated with increased caloric intake and subsequent obesity in later life, which may be mediated by (a combination of) decreased neural cognitive control over food intake, decreased neural food reward…
To evaluate efficacy of topical treatment with coal tar compared to topical treatment with corticosteroids in children aged 1 to <16 years with moderate to severe AD, based on the percentage change in Eczema Area and Severity Index (EASI) at…
Part 1: To develop a child friendly method to balance bilateral input with regard to loudness and to assess the effect of this so-called bilateral loudness balancing on speech perception in noise and localization. This child friendly method with…
The aim of the FLOW project is to unravel immunological mechanisms driving inhibitor development in NSHA patients and HA carriers. We will focus on the association between (1) surgery , (2) intensive treatment, and (3) immunological biomarkers and…
Primary Objective: Primary aim of this study is to evaluate the effectiveness and cost-effectiveness of D(o)epression Blended in clinical practice in reducing depressive symptoms and disorders in clinically depressed adolescents. The modern and…
The objective is to find the most effective combination of wearable devices to accurately reflect paediatric asthma control in a home monitoring situation, by studying the relation of the home-measured signals to the currently used exercise…
The main objective of this study is to investigate the developmental trajectory of the perception of voice characteristics in children and how it relates to the recognition of gender, emotions, and linguistic processing in CI children, in comparison…
To assess treatment results of light trauma care in the primary care setting, in comparison to light trauma care in the secondary care setting. In addition, we aim to study time consumption and costs.
The primary objective is to evaluate the efficacy of CCX168 (avacopan) to induce and sustain remission in patients with active anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), when used in combination with cyclophosphamide…
First, to compare MLP children with FT and with EP peers regarding intelligence at age 14 to 15 years. Second, to compare MLP children with FT and with EP peers regarding health, health-related behaviors, growth measures, blood pressure, pubertal…
The primary objective is to demonstrate the non-inferiority of edoxaban to standard of care (SOC; including low molecular weight heparin (LMWH), or vitamin K antagonist (VKA)) in the treatment and secondary prevention of VTE in pediatric subjects…
The objective of this study is to investigate the association of the residual galactose oxidation capacity (measured in vivo and in vitro) and of galactosylation abnormalities with outcome in patients with galactosemia.
The goal of the study is to examine the effectiveness of emotion-regulation training for adolescents with externalizing problem behaviors and an (above) average intelligence (target group A) or mild to borderline intellectual disability (target…