907 results
To get insight into the prevalence of a whole range of psychiatric symptoms of parents of children who have been admitted to an outpatient clinic for child and adolescent psychiatry for various psychiatric symptoms and the parent-offspring…
1. To determine demographic, clinical, and brain morphological and functional predictors for IST, and; 2. To examine their associations with the level of increase of seizure threshold (*ST) during the ECT course, as measured at every sixth ECT-…
To evaluate whether cognitive function of formerly preeclamptics is diminished and correlated with dynamic cerebrovascular control properties using non-invasive measuring techniques (dynamic cerebral autoregulation, neurovascular coupling). Question…
To establish the pharmacokinetic profiles of saliva and plasma concentration of 10 mg MPH-IR and 18 mg MPH-OROS in healthy volunteers; to investigate whether there is a correlation between saliva- and plasma levels of MPH-IR and MPH-OROS, and if…
The relationship between sleep disorders and (reactive) aggression in forensic psychiatric patients.
The primary objective of this study is to examine the relationship between sleep disorders and (reactive) aggression in forensic psychiatric patients in the Forensic Psychiatric Center Dr. S. van Mesdag in Groningen. In addition to this,…
The aim of this pilot is to evaluate the feasibility of a web-based self-help course for social anxiety in adolescents. We also hope to get an indication of the effectiveness of the course. Are their social anxiety symptoms diminished after…
Do trauma cues trigger more craving in individuals with substance dependency and PTSD in comparison with substance dependent individuals without PTSD? If so, is this effect trauma-specific or are SUD-patients with PTSD more sensitive to general…
The object of this study is to determine variables associated with therapy-success of a cognitive behavioral self help intervention for insomnia.
The primary objective of the study is to determine whether people scoring higher on grief rumination show a stronger vigilance-avoidance pattern of attention for loss-related stimuli. We expect grief rumination will show a positive linear…
The main aim of this study is to collect normative data on the RANDI for several age groups.
Main objectives: (1) To identify genetic, environmental and clinical determinants of psychosis vulnerability and onset. (2) To assess neural systems and behavioural substrates mediating gene environment interactions. (3) To test for gene-…
The global aim of the proposal is to expand our knowledge on the functioning of the fronto-striatal system and the relation to behavioral rigidity, and how these are affected by dopaminergic modulation. The specific aim is to study the effects of…
Primary:to explore the routes and rates of elimination of [14C]-radio labeled RO5200628 after oral administrationto determine the pharmacokinetics of total drug related material, RO5200628and its metabolites as appropriateSecundary:to investigate…
The general objective of HELIUS is to describe (trends in) patterns of chronic conditions across six ethnic groups over time, and to unravel the causes of (the unequal burden) of chronic diseases across ethnic groups, with an emphasis on…
Primary:- to assess the pharmacokinetics of the study drug and total radioactivity (TRA) and the routes and extent of excretion of drug-derived material after administration of a single 3 mg oral dose of 14C- labeled study drug in healthy male…
Measuring the effects of light therapy during hemodialysis on objective en subjective sleep parameters, sleepiness during dialysis, mood and melatonin rhythm. De results of this pilot study can be used to design a larger study on light therapy in…
The goal of the present study is to describe this unique sample on the basis of dossier analysis at the time of referral and reassess all individuals for follow up. VERPLAATST: The main objective of this study is to assess long-term outcome of…
Our primary aim is to test whether SFT is a suitable and effective treatment for chronic depression in terms of acute effects and the prevention of early relapse. Our secondary aim is to identify the underlying mechanisms of change in SFT that lead…
part 1: to assess the absolute bioavailability of SCH900777part 2: to characterize the absorption, metabolism and excretion of SCH 900777to evaluate the safety and tolerability of SCH 900777 in healthy subjects