40 results
The primary objective of this study is to analyse the microenvironment of the tumour, (sentinel) lymph nodes (i.e. various T-cell populations, antigen presenting cells and myeloid-derived suppressor cells) in patients with vulvar carcinoma. The…
The primary objective of this study is to analyse the microenvironment of the primary tumour and sentinel and non-sentinel lymph node(s) (i.e. various T-cell populations, antigen presenting cells and myeloid-derived suppressor cells) in patients…
Objective: determine whether a Likert-type scale scoring system, specified for skin irritation reactions (erythema, itching, burning sensation of skin and general irritation of skin) can function as a tool to score the radiation-induced dermatitis…
The objective of the study is to measure the extend of voiding symptoms and bother of the urinary tract in young females and to analyse flow patterns and post void residual.
Our main objective is to compare the effects of weak and strong food temptations on the activation of reward and conflict areas in the brain.
Primary Objective• To demonstrate feasibility of measuring deuterium incorporation into galactosylceramides within the quantitation limits of the assay, in human CSF after chronic dosing of D2O.• To develop a mathematical model to allow estimation…
The Objective of this study is to validate the new developed sensor fotoplethysmografie (MPA-16), that later can be used to better understand the local vasculature. And determining the feasibility / applicability of this test setup for patients.
The main objective of the study is to monitor the factors effecting success of PDT, namely oxygen, photosensitizer concentration and, light dose before and during illumination to gather data that can be clinically correlated and later implemented.
The objective of this study is to determine whether the dichotomization in good and poor outcome by the composite scale, corresponds better with the parents' and doctor's opinion on the outcome than the PSOM. The composite scale willl be…
Our investigation aims at the translation of heart valve tissue engineering from the laboratory bench to clinical application. In the present study, we compare different cell sources in their ability to form heart valve tissue. Furthermore, as we…
Collecting T cells of 2 stage IV melanoma patients via leucapheresis for conducting test runs in order to develop a gene therapy study.
Study of zoonotic protozoan infection in animal keepers. The findings will provide data which can be used to design better health polici for NHP and animal keepers.
We want to get a better picture about the causes of math difficulties
Our purpose is to establish whether the frequently observed absence of tumor regression in the presence of infiltrating T lymphocytes is due to a lack of T cell effector function or due to an inhibitory influence of the tumor microenvironment on T…
In this project, we will examine whether the simultaneous recording of ERPs and fMRI during the adapted grating task results in data of sufficient quality. More specifically, we would like to know 1) whether the components normally observed in the…
The main objective of the current study is to investigate the significance of default-mode network activation. We aim to answer the question whether this activity reflects meaningful cognitive activity or merely the controlling of physiological…
Analyse the correlation between baseline MSC level in peripheral blood from cancer patients and their primary tumor type.
To obtain comprehension in the development of quality of life during and after clinical rehabilitation and the factors that influence it. This leads to the following questions:Primary questions(1) What is the progress of mental health and well-being…
To investigate the causal involvement of the ralPFC in the offset of fear (study 1) and SSRT (study 2) by temporally inhibiting this area using transcranial magnetic stimulation (TMS).
* Genotyping of the full GBA1 gene in people with Parkinson*s Disease, assessed as wildtype (GBA-) or containing a mutation (GBA+); the specific mutation will be recorded as well. * Assessing the presence of 7 known PD-causing mutations in the LRRK2…