20 results
The primary aim of our study is to evaluate safety and toxicity of ex vivo-expanded NK cell infusions following a non-myeloablative conditioning regimen in elderly AML patients who are no candidates for allogeneic SCT. Moreover there is also a…
To compare the effectiveness of PVI and VATS-PVI. Secondary objectives are to compare the duration of hospitalisation, quality of Life, cost and to compare the satisfaction of the patients.
The primary objective of the REBEL study is to collect data needed to design control policies to diminish the spread of ESBL-producing Gram negative bacteria in the Dutch population.
Aim of the study is to evaluate if the optical tissue stylet technology can discriminate tissues that are relevant to recognize for interventional pain procedures.
The primary objective of this study is to develop reliable signal analyzing methods for the monitoring of brain function in adult patients at risk for deterioration of brain function, (non)convulsive seizures or cerebral ischemia. The methods will…
The purposes of this study are to study the effects of low-frequency NMES, high-frequency NMES and resistance training on health status, exercise tolerance and muscle strength in patients with COPD.
Primary objective:To assess the effect of implant choice (CS vs SHS) on gait pattern in patients that are >1 year after surgical treatment for a femoral neck fracture.Secondary objectives1. To assess the effect of implant choice (CS vs SHS)…
First objective; to document the existence and to categorize vocal fold pathology after short term intubation and to study voice related patient complaints after short term intubation. Second and third objective; to study the pattern/type of injury…
The primary objective of this study is to determine the effects of aliskiren, as compared to ramipril, on renal hemodynamics in overweight/obese and hypertensive patients.
1. To quantify the influence of propofol on the distribution, redistribution and elimination of ketamine and to evaluate the importance of hemodynamic parameters on the pharmacokinetics of ketamine.2. To quantify the influence of ketamine on the…
To compare one dose of the short acting tropicamide combined with one dose of the longer acting cyclopentolate (c+t) with a double dose of the longer acting cyclopentolate (c+c). To develop a cycloplegics protocol that garantees optimal refractieve…
Primary Objective: • To study the clinical efficacy of local treatment with monobenzone and imiquimod cream on cutaneous metastases in stage III-IV melanoma patients Secondary Objective• To study the induction of local tumor-specific immunity by MI…
Investigate the effectiveness of the use of telecardiology and biomarkers in general practice. Invastigate if the number of correctly diagnosed patients that will be sent to the hospital will increase
Study phase 1: In patients with BO undergoing work-up endoscopy for early neoplasia, we aim to develop a classification to evaluate fluorescence spectroscopy of neoplastic and non-neoplastic lesions in Barrett epithelium, as used in phase 2.Study…
The primary objective of this randomized trial is to assess the Safety and efficacy of the Genous Bio-engineered R Stent* pre-dilated with paclitaxel-eluting balloon (Pantera®) versus the Genous Bio-engineered R Stent* pre-dilated with non drug…
To analyze the relation between reduction in BMI and reduction in the exercise induced fall of FEV1 after a diet-period of 6 weeks. Secondary we analyze the relation between reduction in BMI and the recovery of the lungfunction to baseline (measured…
The general objective of HELIUS is to describe (trends in) patterns of chronic conditions across six ethnic groups over time, and to unravel the causes of (the unequal burden) of chronic diseases across ethnic groups, with an emphasis on…
Efficacy of sorafenib in NSCLC with a K-RAS mutation as determined by the Disease Control Rate at 6 weeks
What does the non-specific cytokine response contribute to the prediction of prosthesis fixation (expressed in MTPM after 1 years), compared with simple patient characteristics?
To study the feasibility of reducing the dose of preoperative radiotherapy in MLS from 50Gy to 36Gy while maintaining comparable clinicopathological responses.