29 results
The aim of this research is to improve the understanding of the coagulation system through a detailed characterization and quantification of biosynthesis and expression of several coagulation proteins in BOECs. The data obtained in the study will be…
1). Evaluate the expression of the genes encoding the enzymes that modify histones and DNA during monocyte differentiation in MS.2). Consequences of monocyte dysfunction for migration and cytokine/chemokine production.
The objective of the present study is to investigate the course of psychosocial functioning in stroke patients and their partners, during the first 2 years post-stroke, to investigate factors predicting psychosocial functioning in stroke patients…
To assess intra- and interpatient variability of plasma Mg concentration before and after hemodialysis.
- To correlate clinical and biochemical cardiovascular risk factors to arterial wall 18-FDG uptake in large artery atherosclerotic lesions.- To correlate inflammatory markers to arterial wall 18-FDG uptake in large artery atherosclerotic lesions.
In the past there has been little attention for quality of life, of which sexuality is an important part, in both scientific research and in clinical practice. Nowadays things are changing and talking and thinking about the sexual functioning and…
The objective of the current study is to determine whether cognitive, emotional, behavioural, and personality explain individual difference in fatigue symptomatology. Furthermore, this study wants to examine whether fatigue is a risk marker for…
To examine whether a self-help psychological intervention program, based on relaxation, changing negative coping styles and finding new goals would be useful for people with PAD.
In the presented study we would like to investigate the genetic background of the AAA with a twofould objective, namely the possibility of presymptomatic diagnosis of the AAA and the definition of molecular mechanism as possible therapeutic targets.
The aim of this proposal is to investigate the potential use and value of experienced utility, as measured by the ESM and the DRM, in the economic evaluation of health care.Research question:1. What are the differences between the utilities measured…
Primary research question:To evaluate the impact of open versus endovascular invasive treatment in different types of surgery (AAA, CEA, LLR) on health status. Secondary research questions:To examine the prognostic impact of quality of life in PAD…
1. To adjust and validate our forearm model for ischemia reperfusion injury, in order to used it for assessment of ischemic postconditioning.To adjust our forearm model for ischemia reperfusion injury, in order to used it for assessment of ischemia…
This quantitative research project was preceded by a qualitative study (Sexuality in people with a limb amputation and their partner: a qualitative study; METc 2010/179). The aims of the current study are to explore:- which sexual problems occur in…
A study will be conducted to investigate whether screening for PE and growth restriction not associated with PE in the Dutch setting is feasible.
The aim of the present study is to investigate cerebral vasoreactivity in response to lower body negative pressure in young and elderly healthy men, as a measure of cerebral autoregulatory responsiveness.
Primary objective* To investigate the correlation between cutaneous microcirculation (using LSCI), finger and toe pressures and shunt flow in hemodialysis patients.Secondary objectives* To investigate the variability in basal flow measured with LSCI…
The main objective is to investigate whether local mast cell activation correlates with an unstable phenotype of the atherosclerotic plaque.Secondary objectives are: 1. To investigate whether elevated systemic mast cell markers are correlated to…
The present study will investigate the association between Blood-Brain Barrier leakage and cognitive aging.Primary research question:1. a. Is stronger BBB leakage associated with greater decline in episodic memory?b. Post-hoc explorative analyses…
To enhance our knowledge concerning the effectiveness of tDCS in the rehabilitation of stroke patients. Next to this, the results will also contribute to our knowledge concerning the role of the parietal cortex in episodic memory and attentional…
The objective of this study is to assess the prognostic value of early perfusion changes and infarct evolution detected with magnetic resonance imaging (MRI) acquired directly after EVT.