10 results
We hypothesize that the amount of physical activity correlates with insulin-induced microvascular recruitment during free-fatty acid infusion in skeletal muscle as well as in the heart. In this study we aim to test this hypothesis.
1. Do body fatness and/or body fat distribution show a linear association withmicrovascular function in normal as well as IGT subjects?2. Is the effect of body composition on the microvasculature mediated by alteredadipokine profile, low-grade…
We aim to study the role of PVAT in regulation of vascular function, tissue perfusion and glucose uptake in muscle. We hypothesize that PVAT determines insulin-induced vasoreactivity when studied ex vivo and correlates with insulin-induced…
We aim to study the role of PVAT in regulation of vascular function, tissue perfusion and glucose uptake in muscle. We hypothesize that PVAT determines insulin-induced vasoreactivity when studied ex vivo and correlates with insulin-induced…
Aim 1: Confirm the hypothesis that the IgG4 qPCR test score correlates with disease activity in vasculitis as observed in the pilot study. Aim 2: Study IgG4-expressing B-cells from blood of vasculitis patients to understand their role in the…
The primary objective is to validate the LSCI against the LDPI in the assessment of the forehead DBF induced by capsaicin application and saline iontophoresis.
(1) To develop patient-specific hemodynamic models of arteriovenous grafts at multiple time points after surgery, thereby including venous outflow stenosis; (2) to determine the critical stenosis severity at which the arteriovenous graft is at risk…
Primary objectives are displayed here.Part 1: Establish the effect of early life cardiovascular risk factors on pre-clinical atherosclerosis in adolescents.Part 2: Identify the impact of diminished early life lung function on lung function during…
1. Define in detail how autoantibodies and changes in the B cell compartment correlate with different stages of clinical microvascular damage in SSc.2. Determine which soluble factors, including autoantibodies, in SSc-blood of clinically well-…
The main goal is to define whether macrophages from patients with AGN induce T-cell activation and migration due to their pro-inflammatory phenotype.