17 results
Goal of our study is to compare the CO measuments by the Oesophageal Doppler Monitor (ODM, Cardio Q) with the TPTD technique (PiCCO) and to determine reliability of the ODM in absolute CO values and as a trend monitor. A validation study comparing…
Investigate the incidence and severity of early coagulopathy in severe sepsis and septic shock patients and investigate the correlation between these coagulation disturbances and the incidence and severity of microvascular changes.
To study dose-dependent hemodynamic and microcirculatory changes during oxygen supply in mechanically ventilated ICU patients.
To detect incipient central hypovolemia preceding symptomatic cerebral hypoperfusion by machine learning models trained on realistic physiological models.
The primary goal of this study is to determine if the use of multi-site NIRS-monitoring in newborn infants at risk of circulatory failure could lead to a better diagnosis, treatment and outcome in these infants compared to the use of conventional…
To assess the effectiveness of an additional cardiovascular assessment and intervention to a multidisciplinary falls-intervention.
The aim of the present study is to investigate cerebral vasoreactivity in response to lower body negative pressure in young and elderly healthy men, as a measure of cerebral autoregulatory responsiveness.
To investigate if norepinephrine is safe and effective in increasing blood pressure and systemic blood flow in premature and full-term neonates with shock and/or hypotension.
The main objective of the study is to determine the diagnostic and prognostic added value of careful history taking and Nexfin in the initial evaluation of (pre-) syncope patients in the ED and the follow-up period. The secondary objective is to…
To compare the accuracy of the above-mentioned methods in patients admitted to the ward or intensive care unit in estimating CVP and to investigate the correlation between the different methods.
In this study, we aim to investigate the postoperative time course of microcirculatory parameters in patients admitted to the ICU after cardiothoracic surgery with and without circulatory shock. Secondary objectives:* To study the postoperative time…
To determine the effect of SaO2 and PaO2 levels on mitoPO2 and markers of oxygen delivery and consumption in healthy human volunteers.
The primary aim of the study is to determine the incidence of perioperative hypovolemia in the elderly patient scheduled for major surgery, and how this relates to postoperative complications.
In this explorative-study, we aim to investigate the relation between cDPP3 release kinetics and clinical outcome parameters in OHCA patients after ICU admission. This could lead to the identification of a new predictive marker, a potential…
To determine the accuracy of cardiac output (CO), estimated by carotid blood flow measurements using ultrasound, compared to CO estimated by PICCO thermodilution, or invasive or non-invasive pulse-contour analysis.
Primary Objective: To assess the incidence of microcirculatory perfusion alterations, according to a predefined arbitrary cut off value, in patients with severe burns injury (>15%TBSA) during standard resuscitation in the first 24 hours.
Peroperative assessment of the heart's microcirculation during coronary arterial bypass surgery (CABG) with incident dark filed imaging