62 results
To describe the treatment expectations of patients with a pituitary tumor undergoing treatment as well as patients' evaluation of the perioperative trajectory. Moreover, we will determine the fulfilment of expectations and clinical outcomes…
To determine long-term radiological and clinical outcome of a muscle-sparing surgical technique for posterior decompression of the cervical spinal cord (cervical split laminectomy).
In this study one of the goals is to compare 7 tesla MRI with 3 tesla MRI in terms of lesion detection in epilepsy patients and depiction of specific dysplasia-related imaging characteristics. Furthermore, resected tissue will be scanned ex-vivo at…
Our first goal is collecting high quality raw EEG waves, - measured simultaneously on multiple locations of the brain - during a pharmacological reproducible anesthesia. The goal is to observe EEG patterns that allow the development of technology to…
The objective of this pilot study is to investigate the feasibility of using the Clip system in a human setting in creating an intracranial arteriotomy in a non-occlusive, sutureless fashion. Although the focus is on the technical success of the…
Determination of prognostic value of intraoperative growth hormone levels on postoperative curation for acromegaly in patients undergoing transsphenoidal resection of pituitary adenoma.
A study on extent-related outcome and complications for degenerative cervical spinal disease has not yet been performed. Results of this study may form the basis for a guideline regarding the extent of fixation in degenerative cervical spinal…
Whether the DNIC test can be used to make a prediction of postoperative pain perception and consumption of analgesics after live donor nephrectomy.
Primary Objectives:• show effectiveness of the SMSC instrument in 3D correction of the spine prior to placement of the implants.The hypothesis is that to achieve de-rotation of the spine without failure of the pedicle screws, de-rotation has to be…
Our overall aim is to create a cost effective non-invasive method of pre-surgical assessment of language and memory function using MEG scanning. We propose a research project with the key objective to evaluate the effectiveness of a Dutch…
primary objective:-to define the optimal glucose intake by quantifying endogenous glucose production and fractional gluconeogenesis in critically ill children.secundary objectives:-determine glucose utilization in relation with exogenous glucose…
Optical Tissue Stylet - descriptive observational study into paravertebral space detection in humans
The primary objective of the trial is to investigate if the optical tissue stylet technology can reliably identify the thoracic paravertebral space. Diffuse reflectance spectra will be acquired during needle advancement, with custom-made needle…
The effect of the intervention on pain an regain of function in de affected extremity. This will be quantified in multiple questionnaires at baseline and three follow-up points, and by clinical evaulation of the hand function at baseline and two…
This study is dedicated to obtain accurate broadband (400 - 1830nm) diffuse reflectance spectra of human nerve tissue in vivo (which knowledge creates possibilities to design useful imaging devices).
The primary objective is to avoid cognitive and affective side effects and maintain the beneficial motor effects by selective stimulation of the STN motor part. With the Select Stim project we want to improve the classical operation procedure, in…
The primary endpoint of this feasibility study is the technical success of positioning the SLIDE device to verify the speed and ease of use without unexpected device related adverse events. A technical success is defined that the SLIDE device was…
Does anesthesia itself or transition of anesthesia to an awake state and vice versa lead to changes in the lactate/pyruvate ratio, glucose, glycerol and glutamate concentration as measured in the brain interstitial fluid?Are the metabolic…
To examine the effect of surgical trauma on mucosal perfusion, intestinal epithelial damage, the inflammatory response and potentially sepsis, following surgery remote to the abdomen in adults, children and neonates,
The main goal of this study is to map the functional anatomy of the anterior optic radiations by correlating the visual field defects to the surgical defects in Meyer*s loop in epilepsy patients after temporal lobectomy.
The primary objective of this study is to characterize functional brain networks in patients considered for (i) epilepsy surgery and (ii) tumour surgery with epilepsy surgery techniques. Characterization will be done preoperatively (MEG), during…