15 results
To assess Bone Material Strength (BMS) in patients with acromegaly with fractures and without fractures.
Primary objective: Assessment of the value of the short-term (2 weeks) response of IGF-I (peak IGF-I SDS) to GH in a dosage of 1.4 mg/m2/day (as part of a dose-escalation IGF-I generation test) in comparison to baseline IGF-I to predict the 1 year…
The primary objective of this study is to assess the relation between the short term metabolic changes after start of rhGH therapy and the long term change in height SDS after one year of treatment. Secondly, we want to assess the effects of GH on…
To investigate if there is a correlation between the peak GH concentrations after ingestion of gelatin protein and the peak GH concentrations after the two standard tests (GHST) in order to discriminate between GHD and non-GHD. To investigate the…
1) Follow-up study of project 2011_371:To determine whether the 27 children found in this study actually had a central hypothyroidism, by complementing the existing data with details from the medical records. The data used in the first study were…
To document cardiac function before and after treatment of CS.
Primary objectivesTo evaluate the prevalence, and incidence in yearly intervals, of pituitary insufficiency after cranial irradiation or total body irradiation at long-term follow-up. Secondary objectiveTo evaluate the impact of cranial irradiation…
Comparing the reliability of a dietary-protein test with conventional Growth Hormone Stimulation Tests.
To identify risk factors that might contribute to the development of post-traumatic HHD in children in order to reduce the lag-time between onset and diagnosis for future patients. To investigate the level of functioning and the quality of life of…
(1) To establish the pharmacokinetic profile of clonidine following oral administration in children with suspected GH deficiency. (2) To relate the pharmacokinetics of clonidine to the observed expected (GH-response, cortisol response, depth and…
We aim to investigate whether copeptin can be used as an early postoperative marker for development of DI. We will measure copeptin levels in patients just prior to and following transsphenoidal surgery to be able to investigate whether copeptin…
The primary objective of this prospective international multicenter diagnostic study is the comparison of the diagnostic accuracy between copeptin measurement after arginine-stimulation (CAS) and the current best diagnostic test copeptin measurement…
The primary objective of this study is to determine the feasibility of intraoperative fluorescence imaging detection of PitNET tissue during TSS using the VEGF-targeting optical agent bevacizumab-800CW in tumors with a Knosp grade of 3 or 4.…
To record and analyse the electrophysiological properties and differences of the human pituitary gland, i.e. the anterior lobe, posterior lobe and adenoma.