74 results
The primary objective is to set-up a well-defined sandwich ELISA method to measure the levels of Ara h6 in blood after peanut consumption.
Primary Objective: Pilot study to identify the optimal patch test concentration for detecting contact allergy to ME-PPD in subjects with a proven contact allergy to PPD, who may be allergic to ME-PPD. Hypothesis: In this study subjects will be…
De objective of this study is to analyse the effect of exercise on the levels of Ara h6 in the blood after peanut consumption. Next to this we would like to know whether these levels found are in associated with the measure of intestinal…
- Establashing the percentage of patients within a population allergic to house dust mite and/or crustaceans, that can get an allergic reaction from consuming mealworm.- Establashing the risk of sensitization and allergy by handling mealworms and…
To study the immunomodulatory effects of non-digestible oligosaccharides using peripheral blood mononucleated cells isolated from blood of healthy controls and patients with peanut or cow*s milk allergy.
To demonstrate that food elimination therapy based on component-resolved diagnostics is an effective and acceptable treatment for EoO patients.
Primary Objective: To determine minimum and non-provoking doses of soy protein (in mg) for soy allergic individuals Secondary Objective(s): To determine the relevant allergens of soy in soy allergy and to determine the relation between allergen…
Primary objective is to determine the actual occurrence of and risk factors for OCD on the hands of Dutch construction workers.With these new insights into the risk factors for OCD, we aim to develop 1) a new diagnostic tool to be used by…
Primary Objective: To determine for a series of drugs frequently used perioperatively the maximal non irritative concentration in intracutaneous skin testing in healthy volunteers. Secondary Objective(s): To compare the percentage/number of positive…
To trace new onset of food allergy and clinical evolution of already established food allergy, determining frequencies and patterns of tolerance development. Influence of environmental and behaverioural factors will be investigated.
The purposes of this study are to determine a threshold level for soy protein when consumed by soy-allergic individuals.
- To determine the association between peanut sensitization and food related physical symptoms - To determine the association between peanut sensitization and the severity of asthma in children
Objective: Determination of cross-reactivity to a newly developed PPD-derivative (F000175918) in previously PPD-sensitized patients. Hypothesis:Since PPD-derivative F000175918 is categorized as a moderate sensitizer, based on pre-clinical…
Primary: to analyze serum samples of adult EoE patients for IgE reactivity to recombinant allergens of common foods.Secondary: to demonstrate the presence of ILC2 in periferal blood of adult patients with eosinophilic esophagitis Tertiary: To store…
To analyze whether the sensitization profile towards hazelnut, peanut and birch pollen and their major individual allergens can be used to predict whether the hazelnut allergy is associated without/with mild clinical symptoms or severe clinical…
To analyse which allergens within cow's milk, peanut or nuts are most potent in activation of T cells and basophils.
The lifespan of human neutrophils, eosinophils, basophils and monocytes under homeostatic conditions
The results of this study will lead to an improved insight in the lifecycle of these cells and our results will be of importance for more insight in chronic inflammatory diseases. For example, it will improve our ability to interpret the results…
We seek to elucidate the immune mechanism(s) that are relevant for clinical tolerance to inhalant and food allergens. For this purpose, patients suffering from allergy to birch pollen and/or house dust mite who receive routine-SIT will be assessed…
Primary Objective: Difference in gene expression profiles in peripheral blood cells between reactors and non-reactors on a sting challenge with corresponding functional annotation and a naïve Bayes prediction model for patients at risk of a re-…
by improving the understanding of the relationship of CRD to clinical expressions of allergic disease in children, this study aims at generating data that can improve the development of tools that will help the primary or secondary care practitioner…