29 results
To address the hypothesis that a potato derived protease inhibitor cream significantly limits perianal dermatitis in patients after colorectal surgery.
The primary aim is to study colon motility following rectal resection with the construction of a deviating ileostomy in patients that received an enema as bowel preparation. We hypothesise that CTT is halted or decreased, similar as in patients that…
A new surgical device for the creation of compression anastomoses, the ColonRing*, which is nickel- titanium based, has been introduced. Safety and efficacy of the device have been established in previous clinical studies and the device has been…
With this study we aim to determine the feasibility of Smooth Seton placement in patients with perianal fistulas
To explore the extent of inter- and intrafraction anatomical changes of the tumour and surrounding normal tissues, throughout the full course of treatment, and to subsequently assess the impact of these changes on the nominal planned dose. This…
1.To prospectively evaluate the course of anorectal function in IBD patients with perianal lesions2.To establish potential biomarkers to predict the course of anorectal function in IBD patients with perianal lesions
- to establish the long-term alteration of anorectal function in women after promary repair of a third degree obstetrical anal sphincter rupture- to evalute the following complaints in women in late postpartum period after 3rd degree rupture:…
1. To investigate whether we are able to initiate and measure the continence and defecation reflex in healthy human volunteers with our new method. 2. To compare the results of these measurements with those of existing techniques.3. To investigate…
To investigate the feasibility of using L-PRP on anastomosis to prevent septic complications from occuring.
Primary objective of the study is the assessment of the dose limiting toxicity (DLT) and the maximal tolerated dose (MTD) of capecitabine and mitomycin-C with concomitant SIBRT in patients with locally advanced anal carcinoma.Secondary objectives…
The primary efficacy variable is if the TachoSil application was feasible. A feasible application implies that the entire TachoSil adhere, TachoSil covers at least 1 cm beyond the margins of the anastomosis line and if more TachoSil sponges are used…
Evaluation of long-term complaints and problems on medical, surgical, psychological, social-emotional, conditional and motoric area in patients with one or multiple congenital malformations. More knowledge on long-term morbidity will lead to better…
In daily practice there are many treatment modalities for hemorrhoids available. Since many years the rubberband ligation is widly used. Recently there are also positive results reported of the artery ligation procedure. This research aims to…
The long-term research objective is to be able to select rectum cancer patients who could receive a less invasive treatment. If prediction of response is possible, surgery may be avoided when complete response after chemoradiotherapy is expected or…
With this study we aim to determine the feasibility of SuperSeton placement in patients with perianal fistulas.
To assess efficacy of INCMGA00012 in terms of the ORR in participants with locally advanced or metastatic SCAC who have progressed after platinum-based chemotherapy.
The purpose of the present study is to verify and optimize the quality of the MRI-images using balloon dilatation during a 1,5T fMRI-scan with a send/receive head-coil in healthy subjects in Maastricht University Medical Center.The primary aim of…
Our hypothesis is that treatment of peri-anal fistula with laser ablation is associated with equal closure rates compared to current therapies. As secundairy outcome, quality of life, postoperative pain and incontinence will be assessed. The primary…
The aim of this study is to determine feasibility of perineal reconstruction using a gluteal subcutaneous transposition flap (Luna flap) after eAPR for rectal cancer.
With this study we hope to improve the closure rate of perianal Crohn*s fistulas.