64 results
The main objective of this study is to investigate whether HRM is able to predict bolus transport of solids and liquids in the oesophagus as adequately as the gold standard, i.e. videofluoroscopy.
to study the relation between esophageal circular contractions and chest pain episode(s) in treated patients with achalasia by using 24-hour esophageal manometry combined with pH-metry/impedance
Developing an evidence-based guideline for the diagnosis and surgical treatment of children with severe gastro-esophageal reflux disease.
The effect of yoga on pain and quality of life in children with functional abdominal pain (irritable bowel syndrome, functional dyspepsia, functional abdominal pain syndrome).
This study had two objectives:1. which factors determine outcome of treatment of children with functional childhood constipation referred to the outpatient clinic of multidisciplinary treatment clinics in the Netherlands;2. which factors can be…
Primary Objective: To evaluate whether exercise leads to an increase total reflux time. Secondary Objective(s): - To evaluate whether the increase in reflux correlates with: exercise intensity, failure of the LES to act as an effective barrier,…
The aim of this monocenter observational pilot study is to determine the incidence and severity of gastric emptying disorders in patients with a hiatal hernia and to observe the effects of hiatal hernia repair and fundoplication on the gastric…
Comparison of 1. taste and 2. texture/palatability of Metamuci orangel®, Volcolon® and generic orange psyllium.
To evaluate the efficacy of laxatives (polyethylene glycol) versus supplementation of fibers on the incidence of rebleeding in patients hospitalized for colonic diverticular bleeding.
The main objective of the study is to assess the effect of sleep positional therapy, using the LEFT device, on nocturnal gastroesophageal reflux.
The purpose of this investigation is to confirm long-term clinical performance and safety of the InterStim Micro System. The primary objectives of the study will evaluate data at 3 months post-implant; however, subjects will be followed for 2 years…
To investigate the efficacy and the mechanisms of action of an anti-reflux mucosectomy in patients with gastroesophageal reflux disease.
The aim of this study is to describe the difference in function of the anal sphincter, measured with functional ultrasound (4D transperineal ultrasound [TPUS] derived strain), before and after SNM as a treatment for fecal incontinence.Secondary…
To evaluate the feasibility, safety and potential efficacy of acupuncture in children with FC. The results of this study will be used to design a future randomized controlled trial (RCT).
The main objectives of the study are to investigate if sleep positional therapy, using the LEFT smartwatch app, reduces nocturnal gastroesophageal reflux symptoms and can train patients to avoid sleeping in right side position.
The main objective of this study is to examine the reproducibility of provocative tests and single wet swallows by high-resolution manometry in patients with dysphagia and/or reflux complaints
Primary objective: Is het possible to induce fecal urge by pressure on the pelvic floor alone? Secondary objectives: - Is there a difference in the assessment of the rectal sensibility with an air- or a water inflatedballoon in left lateral position…
Primary objectives 1. To evaluate the efficacy, feasibility and safety of G-POEM in patients with symptoms delayed gastric emptying after oesophagectomy with gastric tube reconstruction, based subsequently on the clinical success rate at 3 months,…
To identify which micronutrient deficiencies are most common after surgery for esophagogastric neoplasms and to observe the effect of supplementation.
Primary objective of this study is to assess the responsiveness effect size of the ESM-PROM in examining changes in symptom scores between baseline and post-treatment. Secondary objectives are to identify differences in characteristics between…