13 results
The aim of this international field study is to test the scale structure, reliability, responsiveness to change and validity of the EORTC SHQ-C22 in patients with different cancer diagnoses, at different stages of disease, and with different…
Primary objective: To determine the feasibility, perceived usefulness, and patients' satisfaction regarding occupational rehabilitation during chemotherapy in a clinical setting, consisting of counseling by an occupational physician, and an…
This quantitative research project was preceded by a qualitative study (Sexuality in people with a limb amputation and their partner: a qualitative study; METc 2010/179). The aims of the current study are to explore:- which sexual problems occur in…
Primary objectivesIn all patients included in the studyTo asses whether:- MP-TF activity and MP phenotype is associated with specific types of malignancy.- MP-TF activity and MP phenotype predicts for development of thrombosis.- MP-TF activity and…
In the past there has been little attention for quality of life, of which sexuality is an important part, in both scientific research and in clinical practice. Nowadays things are changing and talking and thinking about the sexual functioning and…
Identifying factors that are involved in the way social support is experienced by the patient when confronted with cancer.
The main objective of this project will be to test the hypothesis that SNP profiles can improve the performance of predictive models for the most frequently reported late RISE, i.e. dysphagia, in HNC patients after curative (CH) RT. Secondary…
To investigate whether a tailored physical activity program that starts early (during curative chemotherapy with cardiovascular toxic potential) is superior in terms of reducing long-term cancer-treatment-related metabolic syndrome and…
Primary Objectives• To evaluate in vivo complement activation after first-time treatment with paclitaxel, liposomal doxorubicin (Caelyx) or other complement-reactogenic compounds• To evaluate ex vivo complement activation after incubation of predose…
We aim to establish the difference in immunological function of HNSCC patients undergoing (chemo)radiation with protons versus photons. These preliminary data are required to follow-up with larger studies to compare the effect of proton (chemo)radio…
To examine the prevalence, risk factors and mechanisms of impaired health outcomes (short- and long-term medical and psychosocial effects and late effects) over time among a population-based sample of AYA cancer patients.Primary Objective: - To…
Primary Objective: We want to further develop and evaluate our patients* specific ex vivo LC organoids in which at least 50% of the obtained tumor samples are viable and proliferating at week 2 and 6.Secondary Objective: We will analyse differences…
The primary objective is to develop a cell therapy production protocol in line with Good Manufacturing Practice (GMP) regulations by which an autologous T-cell product is generated towards tumor-specific neoantigens. The secondary objective is to…