82 results
To determine the clinical value of chronic implantation of an electrode adjacent to the dorsal genital nerve for conditional electrical stimulation in patients with overactive bladder syndrome The aim is to have >60-70% decrease in number of…
To monitor the electric activity of the urinary bladder, and to localize the pacemaker, and the path of electric signal propagation of the detrusor muscle contractions.
To evaluate the efficacy, safety and PK of solifenacin succinate suspension after multiple dose administration.
Research questions:* What is the incidence of UTI*s in patients in Martini General Hospital Groningen and other Santeon hospitals using CIC to empty their bladder?* What is the impact of an UTI on patients*quality of life and on illness related (…
Main objective: To evaluate the outcomes of the PelFIs in patients with OAB; the relation to the clinical efficacy of antimuscarinic treatment and to hyperactivity of the pelvic floor muscles.Secondary objectives:• To asses the efficacy of…
To determine whether rate change is feasible and has a positive influence on the effect of SNS on the symptoms measured with voiding diaries.To investigate whether there are differences between optimal stimulation settings between patients with SNS…
To describe the course of symptoms of BPS/IC after intravesical injection of Botox®.
To determine the performance (safety and effectiveness) of miniaturo*-I for the treatment of urinary urge incontinence.
The objective of this study is to determine whether bilateral sacral nerve stimulation with FSTLP test is more effective than unilateral stimulation, among patients with non obstructive urinary retention.
1-objective: to get insight in objective (urodynamic) and subjective (questionnaire) changes of the lower urinary tract after laparoscopic robot assisted radical prostatectomy, Intensity modulated radiotherapy, I-125 brachytherapy.2-To create…
This study aims to evaluate different techniques for emptying, flushing and filling of the bladder using a bladder catheter in a pilot study, to find and standardise the best technique. This will make FDG-PET/CT suitable for response monitoring of (…
The purpose of this study is to determine if the development of idiopathic scoliosis is related to neuropathic detrusor/sphincter dyssynergia. When bladder and sphincter function are disturbed, adequate therapy can be started in an early phase to…
Objective: To determine whether genotype of the promoter polymorphism is associated with alterations of mRNA expression of the M2 receptor
Primary objective: to study the feasibility and toxicity of the combination of intravesical chemotherapy with Mitomycin C and regional 70 MHz microwave therapySecondary objective: to develop a new bladder catheter with sufficient thermocouples to…
The objective of the study is to ascertain whether the high effect sizes obtained in the previous studies can be explained according to our working hypothesis, i.e. whether the intervention with Urocell is associated with a structural regeneration…
The study is devided in two distinct groups a male and female group: The male group consist of patients with lower urinary tract symptoms (LUTS). The female group consist of patients with the overactive bladder syndrome OAB.The primary objective of…
The research question which needs to be answered is: Is it feasible to recruit in 6 months a minimal of 20 patients with MS and bladder dysfunction to participate in an acupuncture study and are these patients compliant with the treatment and the…
Previous research demonstrates that in some cases, where the tumor of the patient contains a mutation in FGFR3, the mutation can not be detected in urine derived from the same patient. Our hypothesis states that this urine does not contain any tumor…
The current study is set up to validate the working mechanism of the current design of the FemFlow.
To evaluate the safety and efficacy of BOTOX for the treatment of urinary incontinencedue to overactive bladder (OAB) in patients 12 to 17 years of age who have not been adequately managed with anticholinergic therapy. To evaluate the safety and…