13 results
The objective of this study is to evaluate the safety of the AcuFocusTM ACI 7000PDT corneal inlay implanted intra-stromally in emmetropic presbyopes and the effectiveness of the inlay for improvement of near vision.
The study objectives are:- to characterize the biotransformation pathways, the routes and rates of excretion, and total recovery of the 14C-labeled research medication and its radiolabeled metabolites- to characterize the pharmacokinetics (PK) of…
Of each new device it is unknown what the validity is and what the differences (advantages and disadvantages) are compared to the daily used devices.The aim of this study is to answer the question: What is the validity and are the objective benefits…
The main objective is to establish whether a relationship can be demonstrated between the amount of light scattered at the post-operative corneal interface on the one hand and visual acuity and contrast sensitivity on the other. In addition, changes…
Evaluation of pre-operative parameters in order to ascertain the need for a keratoplasty after cataract surgery has been performed in eyes with Fuchs* endothelial dystrophy.
Our research proposal has several aims: 1) We propose to use large-scale genetic studies to identify allelic variants that influence the development of AMD, which will enable the development of diagnostic and prognostic tools in the near future. 2)…
The aim of this study is to use different non-invasieve techniques to measure the spatial distribution of the macular pigment and its possibly relation with retinal structure and contrast sensitivity.
Investigate clinical anomalies in the intraocular tissues, especially the accommodation system, in RDEB patients.
• In this pilot study, PS-OCT is used to image differences in fibrillary ocular structures associated with disease in patients with glaucoma, high myopia, exudative age-related macular degeneration with a suspicion of subretinal fibrosis and…
The goal of this study is to characterize the natural history of STGD1 patients with the appropriate genotype for AON therapy and to identify the best clinical outcomes to measure therapeutic efficacy in clinical trials following completion of this…
To investigate whether mutations in genes associated with lipid metabolism are a risk factor for retinal pathology such as the early formation of drusen
This study has been transitioned to CTIS with ID 2024-512945-18-00 check the CTIS register for the current data. Objectives:Primary: To evaluate the long-term safety of IVT injected pegcetacoplanSecondary:1. To assess changes in the total area of…
Primary Objective: Non- invasive determination of the oxygenation values and the haemoglobin concentration of retinal arteries and veins by means of retinal imaging.