18 results
Primary ObjectiveEstimate the proportion of subjects fulfilling criteria for symptomatic remission (as defined by Andreasen et al.)* following a transition to 12 months* treatment with flexible-dose PP3M in subjects with schizophrenia previously…
The primary aim of this study is threefold. The first objective is to determine whether the SCL and the frequency of non-specific skin conductance response (nsSCRs) measured by the Philips GTEP Emography Bracelet are accurate measures of sympathetic…
The aim of this study is to investigate the feasibility and efficacy of a combined treatment for PTSD and problematic alcohol use (PAU) in a Dutch sample of older patients with PTSD and PAU. Expertise from Brijder addiction care will be shared with…
Main: to examine the comparative and combined effects of aggression replacement training (ART) and Risperidone on aggressive behaviours among adolescents with aggression problems ages 14-21 across clinical and non clinical settingsSecondary: to…
The aim of study I is to compare the two working memory interventions, Cogmed and the intervention developed by the Bascule, in a sample of 100 children with ADHD and working memory deficits, aged between 8 and 12 years old. Effects on working…
Is there an increase in markers of trombogenese (platelet activation, d-dimeer, von willebrandfactor, OPG) in elderly users of antipsychotics six to ten days after the start in comparison to the same markers before start of the antipsychotic…
The main objective of the study is to investigate whether an 8 week MFT for children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD) or Autism Spectrum Disorder (ASD) as well as an 8 week MPT for parents, would be effective in…
Further development and validation of two tools to measure patient progress in the psychiatric health care; the behavioral health status (BHS) questionnaire and the Heart Rate Variability (HRV) measures.
The study aims at finding answers for the following questions:-What changes develop in the perception of patients concerning their daily functioning (inclusing the impact of mental disorders) and how are these changes related to the photo-story they…
- research the efficacy of a new group cbt: 'to control thoughts and feelings'- to indicate whether a randomized controlled study is advisable
It is investigated whether EMDR is effective in reducing post-traumatic stress reactions in young children (1.5 to 8 years), reducing co-morbid emotional and behavioral problems and whether the results will be maintained 3 months after treatment. In…
The overall objective of this study is to use standard clinical measures to explore the safety and effects of open-label manualized MDMA-assisted psychotherapy with a flexible dose of MDMA in participants with severe PTSD, and to serve as an…
The primary objective of the study is to evaluate the long term safety and tolerability of troriluzole as adjunctive therapy in subjects with OCD who have had an inadequate response to standard of care (SOC) treatment for OCD and as defined in the…
Primary Objective: The objectives of this study are to adapt the VRAPT protocol and manuals for people with MBID, and to test the feasibility of VRAPT-ID in a sample of people with MBID and aggressive behavior. Feasibility will be assessed by…
The aim of the proposed research is to test the effect and evaluate the PMT module Safe and Strong, a psychomotor intervention targeting the consequences of sexual abuse in people with MID-BIF and improving the body experience and psychological…
The primary objective of the VRAPT Arousal Pilot Study is to explore the feasibility, appropriateness and acceptability of the developed VRAPT Arousal intervention among forensic psychiatric inpatients and forensic healthcare practitioners working…
The PowerMe study will analyse fatigue characteristics and severity in children and adolescents with mitochondrial myopathy and their families. Then a blended personalized cognitive behaviour therapy program for fatigue will be designed and tested,…
Objective: The objective of this study is to establish the effectiveness and safety of amantadine on emotional lability/irritability, aggression, apathy and impaired executive functioning due to frontal lobe brain injury.