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A Phase 3 Multicenter, Multi-dose, Open-label Maintenance Study to Investigate the Long-term Safety and Efficacy of ZS (Sodium Zirconium Cyclosilicate), an Oral Sorbent, in Subjects with Hyperkalemia

Primary objective of this trial is to generate open-label, long-term (up to 12 months) safety and tolerability data for ZS in subjects with hyperkalaemia (S-K * 5.1 mmol/L)Secondary objectives:* To evaluate the portion of ZS-treated subjects in whom…

Determination of sodium content in sweat in critically ill hypernatremic patients.
Does Non osmotic storage of tissue sodium influence sweating and thermoregulation

To noninvasively investigate the amount and (sodium and chloride) content of sweat in hypernatremic patients in the ICU.

Inulin * a potential preventive dietary supplement against PPI induced hypomagnesemia

Objective: The primary objective is to determine if the dietary fructan-fiber inulin is applicable in PPIH. More specific, it aims to (i) improve the magnesium balance in cases of hypomagnesemic PPI users and (ii) to evaluate if the use of inulin is…

Neurocognitive functioning in school-aged cystinosis patients: general effects of chronic disease or specific deficits?

The aim of the study is to improve the quality of life of cystinosis patients. Part of it forms neuropsychological screening in order to identify specific defects in the neurocognitive development and learning abilities. The results will contribute…

Predictive factors for sarcopenia and malabsorption in high risk surgical oncological patients after cytoreductive surgery and HIPEC procedure

To investigate the predictive factors for sarcopenia in high risk surgical oncological patients undergoing a CRS + HIPEC procedure. The secondary goal is to investigate the predictive factors for malabsorption and the incidence of anastomic leakage…

Hypomagnesemia as mitochondrial disease

The main objective is to investigate whether the variant indeed cause mitochondrial dysfunction leading to the observed phenotype, including characterization of the pathophysiology.

Validation Reseach of Medimate Miniab, Multi Lab-chip 2017

The main objective is to define the self-test performance by means of the Total Error for the Medimate Minilab 2017 for the set of parameters.

Detection of hypovolemia in the elderly patient undergoing surgery

The primary aim of the study is to determine the incidence of perioperative hypovolemia in the elderly patient scheduled for major surgery, and how this relates to postoperative complications.

Role of a simple lung ultrasound score in defining pulmonary edema during early fluid overload in pediatric mechanically ventilated patients

To assess whether pulmonary edema as detected by a lung ultrasound B-line score correlates with the occurrence of early fluid overload and oxygenation failure in mechanically ventilated critically ill children.