49 results
Primary Objective: To study the feasibility of Velocity Selective Arterial Spin Labeling as a non-invasive technique for breast cancer screening by comparing image quality with DCE-MRI.Secondary Objectives: Comparing tumor characteristics and…
The primary objective is to investigate if thermal ablation of breast tumors less than 2cm with < 25% DCIS is effective in terms of the number of tumors in which complete ablation is found on pathology result.
First, the threshold for the biomarkers of 31P-MRS will be determined. These biomarkers can indicate whether a patient with breast cancer benefit from the neoadjuvant chemotherapy (NAC). Then it is determined whether a (combination of) biomarker(s)…
This clinical performance study will evaluate the effectiveness of the Ki 67 IHC MIB-1 pharmDx (Dako Omnis) to identify estrogen receptor (ER)+/human epidermal growth factor receptor 2 (HER2)- early breast cancer patients whose tumours score Ki-67…
Primary Objective: • To investigate the feasibility of utilizing PAI as a means of detecting the SLN in patients with melanoma or breast cancerSecondary Objective(s): • Determine the most effective wavelengths for detecting ICG in PAI• Investigate…
The main purpose is to investigate the safety, pharmacokinetics and feasibility of ONM-100 as an intra-operative optical tracer to detect tumors and metastatic lymph nodes in solid cancers. Moreover, the study will investigate the optimal dose of…
To be able to assess the value of new markers, we first analyze these potential markers in nipple aspirate fluid and blood from healthy women. The main goal of this study is to evaluate the normal expression levels of microRNAs in NAF and blood to…
To develop and evaluate an adaptive MRI-only workflow for the MR-linac treatment in breast cancer patients eligible for APBI, regional lymph node irradiation or a radiotherapy boost on tumor positive lymph nodes. Furthermore, to investigate whether…
Determine the efficacy and safety (using objective response rate) of tremelimumab in patients with advanced solid tumors (UBC, PDAC, TNBC).