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The Prevalence and Genotype of Genital (High-Risk) Human Papillomavirus Infections in Female Renal Transplant Recipients

To study the (high-risk) HPV-infection prevalence and genotype in a cohort of female renal transplant recipients in order to offer adequate follow up for the patients who are infected with high-risk HPV.

Tolerance and immunogenicity of ProCervix, a therapeutic vaccine composed of 2 Human Papillomavirus (HPV) antigens vectored in recombinant adenylate cyclases, in HPV 16 and/or HPV 18 infected women with normal cytology

Primary objective: * Examine the safety and tolerability, both local and general, of ProCervix Solution (escalating doses) and ProCervix Powder in women infected by HPV 16 and/or 18 with normal cytology from Week 0 to Week 10. Secondary objectives…

Follow-up after treatment of Neisseria gonorrhoeae infections, when and how is a test-of-cure to be included in routine? A prospective observational cohort study

The primary objective is: The minimum time in days after treatment for Ng to perform a TOC using NAAT and DNA PCR. Secondary objectives are: Time to clearance per infected location. Host and pathogen related factors associated with time to clearance…

The incidence, prevalence and genotype of genital Human Papillomavirus infections in females before and after renal transplantation.

To determine prevalence of HPV infection before and after renal transplantation. Secondary objectives are to determine the incidence of HPV infections before and after renal transplantation and the genotype of the HPV infections per time point, and…

Contribution of genetic factors to recurrent vulvovaginal candidiasis

This study aims to determine whether variations in genes encoding the most important components of the innate immune system (gene polymorphisms), play a role in the susceptibility to recurrent vulvovaginal candidiasis.

Pharyngeal chlamydia; temporary colonisation or persistent infection?
A prospective observational study

What is the proportion of STI outpatient clinic visitors with a persistent colonisation of chlamydia in the pharynx up until 3 weeks after the first diagnosis based on a NAAT positive chlamydia pharyngeal swab.

high risk HPV detection from urine and self-collected specimens as patient friendly alternative for physician taken smears

The main goal of this technical feasibility study is to investigate with which HPV isolation and detection method urine and the Evalyn Brush can be combined. HPV stability in urine and on the Evalyn Brush will be investigated as it*s unclear how…

A Phase 2, Multicenter Study to Evaluate the Efficacy and Safety Using Autologous Tumor Infiltrating Lymphocytes (LN-145) in Patients with Recurrent, Metastatic, or Persistent Cervical Carcinoma

This study has been transitioned to CTIS with ID 2024-510634-41-00 check the CTIS register for the current data. Cohort 1 - LN-145 monotherapy in patients who have progressed during or following systemic therapy for recurrent, metastatic, or…