14 results
Main objective is to study changes in in vivo blood viscosity during mild therapeutic hypothermia and rewarming in patients after cardiac arrest. Secondary objectives are to study the effects of cooling and rewarming on-Hemodynamic parameters-…
In a randomized controlled trial, the effects of DHCA and ACP during complex neonatal cardiac surgery on organ function and injury will be compared, especially focusing on cerebral damage and neurological outcome. The primary research question is…
The aim of the study is to identify genes that cause early onset Alzheimer dementia, dementia with Lewy bodies and frontotemporal dementia.
1) To compare fTCD with fMRI, in order to reproduce the previously shown high correlate between the two techniques. 2) to compare rTMS with fMRI and subsequently with fTCD.
To perform a genetic study of left-handedness and language lateralization as endophenotypes of schizophrenia. The study will make use of 30 extended multigenerational pedigrees with multiple left-handers from Urk, an isolated population in The…
We aim to investigate, for the first time, differences in frontal activation between healthy elderly people from Okinawa and the Netherlands. We predict that the Western European elderly will show an "MCI-light" pattern, whereas the…
To determine the intra-individual variation of various potential blood based biomarkers on consecutive days or weeks.
To validate analytical parameters of blood-based biomarker methods and assess the influence of pre-analytical blood handling on levels of those biomarkers.
In this project, we will combine cohorts from several countries into a comprehensive retrospective discovery cohort to examine theabove-mentioned markers focusing on sporadic cases and PPD, in addition to a large number ofpathologically confirmed…
To investigate the neurological and neuropsychological sequelae of COVID-19 infection for which ICU or non-ICU hospital admission was necessary in the spring of 2020 and for which ICU admission was necessary in the fall of 2020, and its consequences…
To assess protein-specific synthesis rates neocortex, hippocampus, temporalis muscle, and vastus lateralis muscle using the D2O dosing method.
1. To examine whether there is an increase in (nigro)striatal dopaminergic functioning in individuals of West-African descent relative to those of Dutch descent (assessed in older participants with DAT SPECT and with NM-MRI in the entire sample). (…
Our primary objective is to investigate the relation between atypical IMP and SINDA scores in infancy and symptoms of DCD at 4-5 years of age measured with the Movement Assessment Battery for Children - 2nd edition. The relation will also be…
Assessment of emotion recognition in patients who suffered an ischemic cerebellar stroke in the past 3 years.