14 results
With this study we aim to provide insight in the role of pulmonary RAS in the pathogenesis of ARDS in neonates and children. This study is performed in the context of a comparative study assessing the impact of age on the pulmonary RAS in ARDS. We…
The aim of the current proposal is to investigate the effects of changes in lifestyle, food intake, physical activity and health related behavior during adolescence on development of asthma, allergy and other chronic diseases. Health outcomes that…
The aim of the extended follow-up of the PIAMA cohort is: To investigate changes during the ages of 8 to 11-12 years in lifestyle, nutrition, physical activity and health related attitude and behavior that are relevant to the development of asthma,…
Primary objective is to show the presence of endogenous ligands of TLR4 in the lung of patients being mechanically ventilated in a standardised way with clinical parameters. Secondary objective is to investigate the amount of endogenous ligands of…
The aim of this study is to access the effect of low and high VT (ml/kg) on pulmonary and systemic inflammatory responses and the release of oxygen and nitrogen free radicals in the paediatric patient with and without ALI.
The aims of the current study are to compare available tests for small airway function in asthmatic patients and to assess differences in small airway function between obese and non-obese asthmatic patients.
Trend analyses Of Patient-Specific respiratory Physiologal INteractions for weaning decision support
The primary objective of this study is to investigate the relation between, on the one hand, 1) the balance between the respiratory system mechanics and muscle dynamics, and 2) the balance between the pressure support level and respiratory drive,…
The primary objectives are to study short-term changes in lung function, respiratory symptoms, bronchodilator medication use, and stress in association with short-term changes in woodsmoke exposures in adults suffering from asthma/COPD and healthy…
1. To compare the proinflammatory, profibrotic and osteogenic cytokine profile in BAL fluid between SSc patients without ILD, with limited ILD, and with extensive ILD.2. To compare the proinflammatory, profibrotic and osteogenic differentiation of…
The aim of our study is to establish the long-term course of (recovery of) respiratory muscle strength and exercise capacity in patients who have received * 48 hours of mechanical ventilation and are discharged home.
The primary objective is to characterize the disease behavior of IPF and non-IPF ILD during the peri-diagnostic period.
To better understand the progression of early CF lung disease we aim to study lipid profiles and PMN dysfunction in relation to the severity of early lung disease in infants with CF, using BALF samples and peripheral blood. To optimally study these…
Primary objectives are displayed here.Part 1: Establish the effect of early life cardiovascular risk factors on pre-clinical atherosclerosis in adolescents.Part 2: Identify the impact of diminished early life lung function on lung function during…
To investigate the association of biomarker measurements (NT-proBNP, hsTroponin-T, CKMB, myoglobin, GDF-15, CRP, IL-6, IL-10, PCT, galectin-3, ST-2, albumin) during an SBT with extubation failure in mechanically ventilated ICU patients.