710 results
Primary:The primary objective is to evaluate the safety profile of an adjuvated Tb subunit vaccine (CAF01) administered in 50 µg Ag85B-Esat-6 alone, 50 µg Ag85B-Esat-6 alone with three escalating CAF01 dose levels, to four groups of healthy…
The aim of the current study is to:1. Determine the incidence of CIN after introduction of preventive measures.2. Describe changes in the course of biomarkers serum creatinine, microalbumin and microglobulin related to intravenous ICM administration…
In deze studie zal de nauwkeurigheid van peroperatieve meting van de cuppositie door een nieuw ontworpen, onlangs gepatenteerd, meetinstrument worden onderzocht. In de toekomst kan, indien het meetinstrument betrouwbaar blijkt, peroperatief de…
Objective of the study is to test the effects of two different interventions during the nightshift on alertness and performance and on sleep quality and health complaints in general. The interventions are short exposure to light or taking a powernap…
Main objective is to investigate if low molecular weight fraction of edible mushroom Shiitake extract possesses clinically relevant caries preventive properties
In this study we will be looking at the effects of the different administration routes on release of satiety hormones by the small intestine.
To monitor the thermoregulatory reponse and the disturbances of the fluid- and electrolyte balance during a marathon. Moreover the incidence of hyperthermia and dehydration is determined, whilst the fluid balance of participants with and without…
Currently, no established risk factor profile for developing arterial cardiovascular events after an acute unprovoked PE exists and is carried out in general practice. The aim of our project is to prospectively study the relation between presence…
This pilot study investigates the feasability of a randomised controlled trial investigating whether the treatment of type 2 diabetes mellitus in people of 80 years and older should be retargeted to optimise quality of life instead of blood glucose…
to identify high risk groups in need for more specific and appropriate guidance. Also to provide adequate counselling and help.
The food consumption survey aims to provide insight in the intake of energy, macro and micronutrients, and foodgroups by non-institutionalized elderly people (age 70 y and over) and the percentage of this population group that meets the nutritional…
Our main objective is to determine the effect of HO-1 induction by heme arginate infusion on insulin resistance and endothelial dysfunction related to MetS. Secondary objectives are to determine the effect on adipose tissue, adiponectin plasma level…
2.1 Primary Objective: To evaluate the feasibility of RenalGuard for diuresis-guided fluid replacement therapy (ability to match in and output) (time to desired diuresis>200ml/hour) To evaluate the safety of forced diuresis and fluid…
In this investigation we want to determine if stimulation of the nerve on each side of the neck that leads to the muscles that make the shoudlers shrug is possible in babies. This can possibly prevent a birth lesion of the barchial plexus in the…
The determination of the energy expenditure in wheelchair-bound children in rest, during daily activities, and during therapeutic horseback riding.
To evaluate the cost-effectiveness the current ruling widespread Royal Dutch Physiotherapy Association guideline, in which the combined use of braces and proprioceptive training after ankle sprain treatment is advocated (usual care), against the use…
1. To investigate the presence of risk factors for CVD (i.e. overweight/ obesity, hypertension, diabetes and dyslipidemia,) among the Ghanaian population in Amsterdam.a) To investigate levels of detection, treatment and control of hypertension among…
The objective of this study is to test whether meat structure plays an important role in protein digestion, to maximise the amino acid availability and to stimulate the muscle protein growth in elderly people.
• Primary objective: To achieve a 100% infection rate of human volunteers by intradermal injection of aseptic, purified, cryopreserved Pf sporozoites (PfSPZ Challenge). • Secondary objective: To compare parasite kinetics between different doses of…