1656 results
In this study the efficacy of a novel monoclonal antibody on the development of psoriasis in the humanized mouse model will be investigated.This experimental compound will be compared with 2 registered drugs, i.e. Humira en Stelara.
To see if the new drug can prevent development of psoriatic changes in the transplant model of psoriasis
Please see pages 3-5 of the Protocol
The main objective of the study is to monitor the factors effecting success of PDT, namely oxygen, photosensitizer concentration and, light dose before and during illumination to gather data that can be clinically correlated and later implemented.
Investigate how S1 and the premotor cortex modulate the cortico-spinal excitability as measures by single pulse TMS stimulation of M1.
In this study we aim to investigate the long-term results of the prepuberal orchidopexie for the acquired undescended testis. The volume and location of the testis are primary outcome parameters that display the result. This information will…
The primary objective of this study is to determine the long-term clinical course in patients who consulted their general practitioner 6 years ago with a new episode of knee complaints. The secondary objectives of this study are to determine…
The aim of this study is to determine whether subcutaneous administration of insulin detemir, as compared to NPH insulin, leads to a more pronounced effect on brain glucose metabolism and blood flow in brain regions associated with appetite…
Test efficacy of compounds D+E in humanized mouse model of psoriasis.
The main objective of this project is to examine the neural correlates of the motivation to be moral in group contexts. We will address three related issues: how the desire to be seen as moral affects people*s self-views and motivation to display…
The purpose of this research is the studying the neurobiology of being in love and related aspects, such as age, duration of the relation, differences in sex, jealousy and the ending of a relationship.
Do trauma cues trigger more craving in individuals with substance dependency and PTSD in comparison with substance dependent individuals without PTSD? If so, is this effect trauma-specific or are SUD-patients with PTSD more sensitive to general…
Research GoalsUsing cross-sectional data we will test whether control and affective brain regions follow different developmental time courses. The first study will focus on the development of inhibitory control (stimulus-driven and intentional),…
- To correlate clinical and biochemical cardiovascular risk factors to arterial wall 18-FDG uptake in large artery atherosclerotic lesions.- To correlate inflammatory markers to arterial wall 18-FDG uptake in large artery atherosclerotic lesions.
The main research questions are whether caffeine influences the development of mental fatigue during task performance as reflected in task performance and how caffeine influences the strength of visual selective attention, reflected in…
The primary objective of the study is to determine whether people scoring higher on grief rumination show a stronger vigilance-avoidance pattern of attention for loss-related stimuli. We expect grief rumination will show a positive linear…
Feasibility of laboratory monitoring in community pharmacies by Point-Of-Care testing creatinine and potassium in ambulatory elderly at risk for impaired renal function.
The principle aim of this study is to characterise all of the genetic alterations that are present in different types of breastcancer by comparing the cancer genome to it's matched normal genome.The primary goals of this ICGC project, which…
To investigate the effects of three different methods of finding a suitable recording site for CMAP and three different electrode sizes on CMAP amplitude and its reproducibility
Evaluate the effect of topical steroids on salivary cortisol levels, and assess the correlation between salivary cortisol levels, symptoms of asthma, and lungfunction in children with asthma and/or rhinitis