1648 results
The study will address the feasibility of the shared decision-making (SDM) intervention by (1) analysing the acceptability of the intervention by users (i.e. professionals and patients); (2) assessing the level of implementation; (3) testing…
Most patients undergoing spine surgery with pedicle screw instrumentation will experience insufficient pain relief in the first three days after surgery, whereafter postoperative pain can be managed with conventional, non-opioid analgesics in most…
Objective The objective of this study is to assess which risk scoring model is most cost-effective for the discrimination between benign and malignant ovarian tumors that guides referral decisions for women with ovarian tumors in the Netherlands…
The primary objective of this study is to monitor the muscle activity related to textural hardness of the food during the consumption of liquids, semi-solid and solid food.
The primary objective is to measure and characterize the tonotopy and modulotopy of the primary auditory cortex in normal hearing subjects. Measurements will be performed both during a normal resting state, as well as during the performance of an…
Previous investigations in our lab have provided insight in the requirements for development of such a system and shown the feasibility of the paradigm (Blokland et al., 2011). We have been able to optimize the settings of our proposed system to…
To measure the impact of the two opposite communication styles (warm, empathic and cold, formal) on the neurophysiological changes (endogenous dopamine release) in the human brain using positron emission tomography (PET) neuroimaging. This is an…
Objective 1: to examine the relation in wall thickness and diameter across arteries that are prone (i.e. carotid, femoral, superficial femoral and popliteal) and resistant (i.e. brachial and radial) against atherosclerosis in healthy volunteers and…
In this study we want to apply heavy water labelling to investigate how ageing affects the dynamics of different leukocyte populations.The main objectives of this study are:(A) to get more insight in the dynamics of an ageing immune system, in order…
The Objective of this study is to validate the new developed sensor fotoplethysmografie (MPA-16), that later can be used to better understand the local vasculature. And determining the feasibility / applicability of this test setup for patients.
The purpose of the study is initial validation and item reduction of the draft questionnaire. This information will be used to improve and further develop the questionnaire into an instrument that will adequately measure physical activity in…
Knowledge about the physiological metabolism of SCFAs and the interorgan exchange of SCFAs across different abdominal organs in humans is lacking to some extent.To this end, the following objective will be addressed in the current study: -Determine…
Objective: Primarily, the objective of this study is to assess the role of serotonergic and dopaminergic polymorphisms in fear conditioning. Secondary, we will investigate additional cannabinergic and corticotropinergic polymorphisms in fear-…
The present project aims to determine the role of NE transmission in reactions to environmental change, both behavioral and psychophysiological, in healthy participants.
The goal of this study is to investigate the long term results after transurethral treatment of infravesical obstruction in boys with respect to LUTS, incontinence, urinary tract infections, coping style and quality of life, and possible…
1. To determine the reproducibility and sensitivity of the EC of walking test in boys with DMD, in comparison with the reproducibility and sensitivity of the 6MWT. 2. To evaluate the one-year course of limitations in ambulation among boys with DMD,…
To do pilot research to investigate the possibilities of EEG and eyemovent studies on perceptual and social processing in baby's.
The aepEX monitor provides a DoH index based on (adult) MLAEP values. The aim of this observational study is to evaluate the performance of the aepEX as a measure of DoH in children.
The proposed study aims to evaluate the recommendations of the guideline regarding the wellbeing of the relatives according to the following questions: 1) To what extent are the recommendations of the guideline adhered to? 2) What is the effect of…
Primary objective 1) To determine how modulating the perceived healthiness of a food alters the neural response to pictures of food packages Secondary objectives 1) To determine how modulating the perceived healthiness of a food alters the (…