109 results
A fundamental question in the current research proposal concerns how changes in cognitive and social-emotional behavior are related to functional and anatomical brain development. The current proposal has the objective to (a) understand the neural…
The main objective is to describe the interactions between physical sensory stimulations and high-level prior assumptions that give rise to visual perception. In two secondary objectives, we will advance novel model-based neuroimaging data-analysis…
To improve our insight in chronic pain and to develop methodologies to treat chronic pain.
How does motor fatigue influence the cognitive functioning of patients with MS and how does this interaction compare to that in healthy controls?
Objective: Primarily, the objective of this study is to assess the role of serotonergic and dopaminergic polymorphisms in fear conditioning. Secondary, we will investigate additional cannabinergic and corticotropinergic polymorphisms in fear-…
Overall aim of the study is to investigate which decision-making models for patient participation are used in practice in end-of-life decision-making and how appropriate are these models for different patient groups.Secondary Objective(s): 1. In…
The purpose of this pilot study is twofold: - evaluation of the tumour movement and regression during and short after long course pre-operative therapy for locally advanced rectal cancer in order to develop an integrated or sequential dose…
The primary objective of the REBEL study is to collect data needed to design control policies to diminish the spread of ESBL-producing Gram negative bacteria in the Dutch population.
Is subjective fatigue in patients with MS related to a combination of force reduction during a fatiguing task and depression score?
The aim of this project is to determine optimal communication strategies for prognostic disclosure in the palliative phase of breast cancer from a patient perspective. Study 1: To explore breast cancer survivors*, healthy women*s and oncologists*…
Instrument development for measuring stress, social support and coping in The Netherlands among young children:The aim of the study is to examine whether 3 adjusted questionnaires for children between 6 and 11 years old, show acceptable internal…
Primary Objective:- To determine the incidence of EPI in pancreatic cancer.Secondary Objectives are: 1. To identify the predictive factors for the development of EPI in pancreatic cancer.2. To evaluate the occurrence of nutritional deficiencies in…
The main objective of this study is to determine a pointprevalence of otitis externa. Further, we want to determine the presence of risk factors and to obtain information about how otitis externa is presented by people with an intellectual…
The objective is 1) to examine the effect of an exergaming balance intervention in older adults; 2) evaluate the intrinsic or extrinsic motivation in older adults to join a training intervention using an interactive gaming device.
The primary objective of this study is to understand whether there is a common brain area for representation of the self and ingroup members. To this end, we will acquire behavioral and fMRI data of 24 healthy students of Leiden University (aged 18-…
The purpose of this study is to explore and expand the understanding of the patient's experience of physical limitations in COPD from the perspective of the patient. The information will be used to support the development of a conceptual model…
The aim of this study is to determine the population and functionality dynamics of the microbiota in ileostomy subjects.
The present study aims to get more insight in the neural mechanisms of pain modulation by anxiety. Psychometric scales acquired from two questionnaires assessing pain-related anxiety, will be used to select two groups based on pain-related anxiety…
The aims of this study are: 1. To investigate the difference in body composition, fat distribution, energy expenditure, substrate and dietary fat oxidation in Asians and Caucasians. 2. To investigate the effect of overfeeding a high fat diet on…
1. To determine the 10 year course and outcome of Anorexia Nervosa.2. To explore predictors of outcome in Anorexia Nervosa.