27 results
To evaluate the efficacy of TESE and to describe the risks of the TESE procedure for the men with a four year follow-up of their offspring.
The purpose of this study is to show that participation in an exercise programme will increase the exercise tolerance, musle power and health-related quality of life and will diminish the degree of fatigue in children on dialysis.
To examine the effect of surgical trauma on mucosal perfusion, intestinal epithelial damage, the inflammatory response and potentially sepsis, following surgery remote to the abdomen in adults, children and neonates,
Determine whether temozolomide given during radiation therapy followed by the combination of temozolomide and CCNU as adjuvant therapy results in an improvement in event-free survival compared to historical control cohorts.To further assess the…
The main objective of this research proposal is to 1). develop an on-line monitor for young athletes to prevent them from a systematic overload and to avoid overtraining 2) develop clinical tools to improve diagnostics of overtraining.
The purpose of this study is to determine if the development of idiopathic scoliosis is related to neuropathic detrusor/sphincter dyssynergia. When bladder and sphincter function are disturbed, adequate therapy can be started in an early phase to…
Determine feasibility and reliability of CDFM in relation to the current strategy of intermittent Doppler US examinations for detection of hepatic artery thrombosis.
Revision of the reference values for aerobic capacity in healthy Dutch boys and girls aged 4-13 years using the Bruce treadmill protocol.
To determine the feasibility and applicability of the intervention 'Traject' to improve the participation in work of young adults (16-25 years) with a chronic disorder.
Relevancy of pharmacogenetic testing for optimizing sedative and analgesic drug therapy in critically ill children will be determined. Pharmacogenetic-based, individualized dosing strategies will be developed to optimize drug therapy.
The aim of the study is to describe to what extent the interaction between family environment and specific polymorphisms can predict various aspects of alcohol use (experimenting, regular drinking, problem drinking, drunkenness) among adolescents…
Our project focuses on the function of transporters and deiodinases in the (dys)regulation of intracellular T3 levels in patients with psychomotor retardation and abnormal serum thyroid hormone levels. The main objectives of our study are:1. To…
To develop and evaluate an internet-supported CBT group intervention for adolescents with chronic pain and their parents.
1. To study the possible association between MBL-deficiency and the occurence and severity of infections in MBL-deficient CF patients.2. To study the possible association between MBL-deficiency and the severity of cystic fibrosis.3. To study the…
Objective of the study is to evaluate the long term results of the interventions of the above mentioned deformities.
• Evaluation of the safety, tolerability and immunogenicity of subcutaneous (s.c.) administration of ACZ885 in pediatric subjects with SJIA.• Assessment of the initial efficacy profile (% responder to treatment and time to relapse) according to the…
The objective of this study is to assess the association of genetic polymorphisms known to be involved in coeliac disease with specific clinical phenotypes in coeliac disease.
1. To gain insight into the prevalence and incidence of HIV and other sexually transmitted infections and blood borne infections among visitors of the STI clinic in Amsterdam.2. To gain insight into risk factors and risk behaviour among visitors of…
To elucidate the molecular basis of skin disease.
Reference values of joint mobility of children in the age 4-18 years.