1853 results
To get insight into the prevalence of a whole range of psychiatric symptoms of parents of children who have been admitted to an outpatient clinic for child and adolescent psychiatry for various psychiatric symptoms and the parent-offspring…
1. To determine demographic, clinical, and brain morphological and functional predictors for IST, and; 2. To examine their associations with the level of increase of seizure threshold (*ST) during the ECT course, as measured at every sixth ECT-…
Primary objective1.To determine the characteristics, frequency and severity of vascular, metabolic and hormonal side effects of angiogenesis inhibitors and EGFR inhibitors.Secondary objectives1.To investigate if steroid profile, indol profile,…
First objective; to document the existence and to categorize vocal fold pathology after short term intubation and to study voice related patient complaints after short term intubation. Second and third objective; to study the pattern/type of injury…
Primary objectives:1. To analyze the exact pathogenic mutations in the TCOF1 gene in TCS 2. To determine the severity, prevalence, natural course within the cohort TCS patients and potential metabolic and physical effects of OSAS in TCSSecondary…
We aim to investigate which part of the pulmonary vasculature, the obstructed or non-obstructed, is responsible for the pulmonary vasodilator response.
Our hypothesis is: HBV interferes with the function of intrahepatic innate immune cells, especially NK cells. Since NK cells play a major role in anti-viral immunity and NK cells comprise a large proportion of the intrahepatic immune cells, we would…
The relationship between sleep disorders and (reactive) aggression in forensic psychiatric patients.
The primary objective of this study is to examine the relationship between sleep disorders and (reactive) aggression in forensic psychiatric patients in the Forensic Psychiatric Center Dr. S. van Mesdag in Groningen. In addition to this,…
In this study we aim to validate changes in the pulse pressure after controlled volume loss during blood donation in spontaneously breathing subjects. This validation will contribute to the development of a standardized manner in which the Nexfin…
The aims of this pilot study are to describe the nutritional status of a well-defined group of Dutch RTT girls with complete clinical, molecular and neurophysiological work-up (full description is presented in the section *study population*) and to…
The aim of the represent proposal is twofold, 1. [PHASE 1] the establishment of a human tissue biobank including muscle and blood, and additionally from a subset subset of subjects fat and skin biopsies will be taken. Samples will be distributed…
The primary objective is to assess the extent to which sensory properties of products predict satiation, and to investigate whether expected satiation may change after repeated consumption of the product.
a. To assess the burden of mumps in the student population.b. To describe the risk factors for mumps virus infection (symptomatic and asymptomatic). c. To determine the relative contribution of household transmission and transmission at the party to…
The aim of the present research proposal is:- to investigate the effect of a dysbalance in lipase expression, induced by selective knockdown, on lipase activity, the accumulation of lipid metabolites and insulin signaling in differentiated…
Main objectives: (1) To identify genetic, environmental and clinical determinants of psychosis vulnerability and onset. (2) To assess neural systems and behavioural substrates mediating gene environment interactions. (3) To test for gene-…
The first aim is to identify possible mechanisms which cause nocturnal reflux in obese subjects. Secondary aims are to identify the role of weight reduction on reflux parameters and to identify the relation between anthropometric parameters (BMI and…
To determine the effect of protein status on food preferences and intake.
The aim of this study is to confirm previous findings and examine the functionality of the creatine transporter in RTT girls, at which mutation analysis of the SLC6A8 gene (as a possible cause of an altered functionality of the creatine transporter…
To analyze the relation between reduction in BMI and reduction in the exercise induced fall of FEV1 after a diet-period of 6 weeks. Secondary we analyze the relation between reduction in BMI and the recovery of the lungfunction to baseline (measured…
Evaluate the prevalence, consistency, and genotype distribution of human papillomavirus (HPV) in semen and to examine the exact localization of HPV (i.e., in the seminal fluid and/or on the membrane or cytoplasm of the sperm cell).Evaluate the…