605 results
The study will address the feasibility of the shared decision-making (SDM) intervention by (1) analysing the acceptability of the intervention by users (i.e. professionals and patients); (2) assessing the level of implementation; (3) testing…
Most patients undergoing spine surgery with pedicle screw instrumentation will experience insufficient pain relief in the first three days after surgery, whereafter postoperative pain can be managed with conventional, non-opioid analgesics in most…
Objective The objective of this study is to assess which risk scoring model is most cost-effective for the discrimination between benign and malignant ovarian tumors that guides referral decisions for women with ovarian tumors in the Netherlands…
1) To investigate whether our current respiratory support improves/recruits FRC in preterm infants at birth by measuring changes in FRC in a non-invasive manner.2) To investigate the adequacy of tidal ventilation during respiratory support in…
To describe quality of life, functional outcome, the radiographic results of the modified Stoppa approach.
The goal of this pilot observational cohort study into the relationship between physical activity, nutritional status, fatigue and quality of life in children (4 - 17 years) diagnosed with solid or haematologic malignancies is to gain insight into…
To investigate the percentage of patients with persistent complaints and/or radiological abnormalities after 5 years follow-up after the first visit to the general practitioner or sport physician. 2. To investigate the long term effectiveness of…
To study if, how, and to what extent, cortical reorganization occurs in children with unilateral Cerebral Palsy after mCIMT.
In this study, we first intend to investigate the optimal time point for measurement of hypoxia in esophageal, pancreatic and rectal cancer using 18F-HX4-PET and then assess reproducibility of hypoxia measurements in these tumor types.
We aim to investigate the relation between cortical excitability, GABA concentration and plasticity in the human motor cortex. We plan to modulate the functional integrity the primary motor cortex by using well-known repetitive transcranial magnetic…
The primary objective of this study is to asses the dynamic vaginal pressure profile in asymptomatic women. The secondary objective is to assess vaginal reflexes in asymptomatic women.
To explore the hemodynamic changes during transition at birth by gathering non-invasive physiological data in healthy term infants.
To evaluate the prevalence of femoral head pathology in patients with MPS III.
Primary endpoint will be VEGF-C expression in MPS cells after low and high sodium diet in healthy male subjects.Secondary Objectives:- Secondary endpoint will be blood pressure response (office blood pressure and 24 hour blood pressure) after low…
A systematic investigation of the neurocognitive underpinnings of cognitive development in young children.
to describe neurophysiological characteristics of *writhing* and *fidgety* GMs in typically developing young infants by means of multiple surface EMG recordings and kinematics.
• To study the effect of treatment modalities immunotherapy (anti-PD1 or anti-PDL-1), and targeted therapy (crizotinib, gefitinib or erlotinib) on the size and diversity of lung carcinoma-specific T cell populations as measured by immune assays,…
Objective 1: to examine the relation in wall thickness and diameter across arteries that are prone (i.e. carotid, femoral, superficial femoral and popliteal) and resistant (i.e. brachial and radial) against atherosclerosis in healthy volunteers and…
Investigate how is the motor cortex affected by the observation of a hand lifting a box of different weights.
The primary objective is to measure and characterize the tonotopy and modulotopy of the primary auditory cortex in normal hearing subjects. Measurements will be performed both during a normal resting state, as well as during the performance of an…