327 results
Current clinical practice is to perform response evaluation, i.e. examination under general anesthesia (EUA), routinely at 3 months after the end of treatment in patients who underwent chemoradiation for oropharyngeal cancer. Due the high response…
Submucous fibroids are known to be related to heavy menstrual bleeding (HMB), dysmenorrhea and fertility problems. Transcervical resection of fibroids (TCRM) is a widely implemented treatment for submucous fibroids, to be precise FIGO PALM-COEIN…
This study will use a Randomized Controlled Trial (RCT) to evaluate the effectiveness and underlying mechanisms of the video game Mindlight, a newly developed anxiety-reducing training for children. Mindlight and a control game will be played for…
1. Alcohol marketing influences youth drinking 2. The following factors moderate of mediate the relationship between marketing & drinking: a. Personal relevance of advertisements, b. Sociability, parental guidance in understanding TV and…
Monotherapy with aspirin or oral anticoagulation after TAVI is safer than the addition of clopidogrel for 3 months, without being less clinically beneficial.
We hypothesize that inhalation of helium gas induces release of protective factors in the blood, which can be used to protect different cell types against ischemia/reperfusion injury.
This study focuses on PTSD due to repeated and prolonged interpersonal abuse in childhood (eg sexual and / or physical abuse) within the immediate environment. By using a Randomized controlled design, we examine whether Imaginary Exposure is more…
In this protocol we will study the value of selinexor as the third agent based on its unique mechanism of action and reported synergy with bortezomib in patients with progressive or refractory MM.
Usage of the 'Moveosiphon' sonothermal sink disinfection device prevents leads to a persistant decrease in colonization with multiresistant Pseudomonas aeruginosa
1. A safe and effective treatment protocol for the Vacoped is: Application of the Vacoped in the operating theatre/emergency department, with partial load-bearing up to 20 kg allowed from day 2. Full load bearing is allowed from day 10-14, with a…
This study has 2 primary objectives: 1) To determine the time point of induction of VEGF expression in the tumour tissue of oesophagus carcinomas during chemoradiation. 2) To determine whether the tumour promoting effects of this induction of VEGF…
To investigate whether patients prefer to be approached by mailed questionnaires for annual follow-up assessment after PCI procedures versus telephone interviews or email-based follow-up
The primary objective is to estimate the frequency of subjects with at least one apnoeic episode, defined as respiratory rate ≤6, detected using the respiR8® device for up to 6 hours after surgery. Apnoea is defined as 10 seconds of no breathing…
We hypothesize that age-related changes in hepatic and intestinal drug metabolism affect the pharmacokinetics of paracetamol.
- The incidence of PONV will be higher in the group receiving dexamethasone alone - There will be no significant difference in the incidence of PONV between the two groups receiving two anti-emetic drugs - There will be less postoperative agitation…
The use of a decision support system will increase adherence to the ESC guideline for atrial fibrillation in terms of calculation of bleeding and stroke risk, and accurate anti-thrombotic treatment for stroke prevention.
We hypothesize that adaptation or tuning of the population PKPD model of propofol will decrease the residual error between predicted and measured plasma-concentrations during maintenance of anaesthesia. The adapted PKPD models can also be used…
Low-molecular-weight heparins (LMWHs) are frequently used in the prophylaxis and therapy of venous thromboembolism (VTE) and the prophylaxis of arterial thromboembolism. LMWHs are mainly excreted by the kidneys and may accumulate in patients with…
EUS-guided fiducial placement in pancreatic tumors is a technically successfull and safe procedure. After placement fiducials can be successfully used for highly-accurate delivery of image-guided radiotherapy.