529 results
In primary prostate cancer patients, the exisstence of lymph node metastases is associated with developmment of distant metastases and negatively associated with cancer-specific survival. The performance of an extended lymph node dissection (ePLND…
Life review therapy will have a positive effect on the level of depressive symptoms of nursing home inhabitants.
End stage kidney disease (ESKD) ranks among the most severe chronic non-communicable diseases with an unmet medical need, given the high (between 10% and 20%) and stable annual mortality rates in ESKD patients treated with dialysis. Kidney…
The two strategies (Venlafaxine and subsequent Lithium addition in non-responders to Venlafaxine; Imipramine and subsequent Lithium addition in non-responders to Imipramine) are comparable in efficacy and time to response.
Addition of Partner for Change Outcome Management System (PCOMS) to individual treatment will result in a significant decrease of drop-out compared to individual treatment without PCOMS in a forensic outpatient clinic in the Netherlands. A sub-…
Medication reconciliation using an e-health application is as good as structured medication reconciliation by a pharmacy technician
The development of a computer aided detection (CAD) system might be able to assist endoscopists in the recognition and subsequent characterization of early Barrett's neoplasia, thereby improving efficacy of BE surveillance.
Primary 1. An immediate invasive approach (immediate angiography and revascularization when appropriate) results in a reduction of the combined incidence of death, re-infarction or recurrent ischemia at 30 days follow-up. Secondary 1. An immediate…
Conform components are beneficial for motion coordination and reducing high rim-loads, while non-conform components are beneficial in reducing high humerus–to–scapula impulses (impact forces).
PRP injections are efficacious for symptom reduction and functional improvement compared to placebo injections in the treatment of ankle (talocrural) OA.
To identify high risk patient groups for development of knee osteoarthritis (OA) in a cohort 9-10 years after meniscus, cruciate ligament and cartilage lesions.
Maternal and neonatal vitamin D level play a role on dental development in childhood
Systematic screening for type 2 diabetes in high-risk obese subjects, identified from the general population, can significantly reduce the diabetes-related cardiovascular morbidity and mortality by at least 25% compared with not offering a screening…
Adolescence represents a crucial stage in the maturation of executive functioning (e.g. working memory and inhibition) and mental health (i.e. behavioral and emotional functioning, and self-concept), which both are important predictors of academic…
Hyperthermic intraperitoneal chemotherapy (HIPEC) has become standard of care for patients with peritoneal carcinomatosis of colorectal origin with a low/moderate abdominal disease load. In case of a peritoneal cancer index (PCI) above 20, a HIPEC-…
Electroconvulsive therapy (ECT) is the most effective treatment for severe depressions. Unfortunately, several cognitive side effects with a large pallet of different manifestations and impact often occur. For instance, postictal agitation ((PIA)…
The optimal management of locoregionally advanced NSCLC is evolving. Multimodality treatment is rapidly becoming the most common approach to stage III NSCLC. ASCO guidelines recommend initial chemotherapy (platinum-based, 2 or 3 cycles) combined…
MBSR influences (1) emotional processing and (2) body awareness. The effect of MBSR on emotional processing is (3) mediated by body awareness.
Hypothesis 1: the Groningen ULR and the Provox®2 are the same in terms of the replacement method, the burden on the patient and the convenience of the replacement and of the resistance during phonation. Hypothesis 2: the Groningen ULR has a longer…
We hypothesize that the subjective well-being of individual patients will show improvement after dose reduction compared with baseline, that is, patients will experience more positive affect, less negative affect and higher physical well-being…